[HTML][HTML] Use of direct oral anticoagulants in patients with obesity for treatment and prevention of venous thromboembolism: updated communication from the ISTH …
KA Martin, J Beyer‐Westendorf, BL Davidson… - Journal of Thrombosis …, 2021 - Elsevier
Although direct‐acting oral anticoagulants (DOACs) have widespread first‐line use for
treatment and prevention of venous thromboembolism (VTE), uncertainty remains regarding …
treatment and prevention of venous thromboembolism (VTE), uncertainty remains regarding …
[HTML][HTML] Use of the direct oral anticoagulants in obese patients: guidance from the SSC of the ISTH
K Martin, J Beyer‐Westendorf, BL Davidson… - Journal of Thrombosis …, 2016 - Elsevier
Four direct‐acting oral anticoagulants (DOACs)–the thrombin inhibitor dabigatran, and the
activated factor X (FXa) inhibitors apixaban, edoxaban, and rivaroxaban–are approved in …
activated factor X (FXa) inhibitors apixaban, edoxaban, and rivaroxaban–are approved in …
[HTML][HTML] Association of body weight with efficacy and safety outcomes in phase III randomized controlled trials of direct oral anticoagulants: a systematic review and …
Essentials• The association of body weight and patient‐important outcomes remains
unknown.• Phase III randomized controlled trials of direct oral anticoagulants (DOACs) were …
unknown.• Phase III randomized controlled trials of direct oral anticoagulants (DOACs) were …
Effectiveness and safety of direct oral anticoagulants versus warfarin in obese patients with acute venous thromboembolism
JC Coons, L Albert, A Bejjani… - … : The Journal of Human …, 2020 - Wiley Online Library
Study Objective Studies on the use of direct oral anticoagulants (DOACs) in obese patients
are limited. Current guidelines advise against DOAC use in patients with a body weight …
are limited. Current guidelines advise against DOAC use in patients with a body weight …
[HTML][HTML] Comparative effectiveness and safety of direct oral anticoagulants compared to warfarin in morbidly obese patients with acute venous thromboembolism …
MN Elshafei, MFH Mohamed, A El-Bardissy… - Journal of Thrombosis …, 2021 - Springer
Direct oral anticoagulant (DOAC) agents are becoming the anticoagulation strategy of
choice. However, their use in the treatment of acute venous thromboembolism (VTE) in …
choice. However, their use in the treatment of acute venous thromboembolism (VTE) in …
[HTML][HTML] Peak plasma concentration of direct oral anticoagulants in obese patients weighing over 120 kilograms: a retrospective study
Background Due to a paucity of data on the efficacy and safety of direct oral anticoagulants
(DOACs) in patients with a body mass index> 40 kg/m 2 or a weight> 120 kg, the use of …
(DOACs) in patients with a body mass index> 40 kg/m 2 or a weight> 120 kg, the use of …
Direct oral anticoagulant concentrations in obese and high body weight patients: a cohort study
AC Martin, W Thomas, Z Mahir… - Thrombosis and …, 2021 - thieme-connect.com
Background Direct oral anticoagulants (DOACs) are prescribed for atrial fibrillation (AF) and
venous thromboembolism (VTE) and both occur more frequently in obese patients …
venous thromboembolism (VTE) and both occur more frequently in obese patients …
Efficacy and safety of direct oral factor Xa inhibitors compared with warfarin in patients with morbid obesity: a single-centre, retrospective analysis of chart data
M Kushnir, Y Choi, R Eisenberg, D Rao… - The Lancet …, 2019 - thelancet.com
Background Because studies of direct oral anticoagulants in patients with venous
thromboembolism and non-valvular atrial fibrillation have had minimal representation of …
thromboembolism and non-valvular atrial fibrillation have had minimal representation of …
Rivaroxaban versus warfarin for stroke prevention and venous thromboembolism treatment in extreme obesity and high body weight
IJ Perales, K San Agustin, J DeAngelo… - Annals of …, 2020 - journals.sagepub.com
Background: Limited clinical data exist describing the use of direct-acting oral
anticoagulants (DOACs) in patients with body mass index (BMI)> 40 kg/m2 or body weight> …
anticoagulants (DOACs) in patients with body mass index (BMI)> 40 kg/m2 or body weight> …
[HTML][HTML] Rivaroxaban versus warfarin treatment among morbidly obese patients with venous thromboembolism: comparative effectiveness, safety, and costs
AC Spyropoulos, V Ashton, YW Chen, B Wu… - Thrombosis research, 2019 - Elsevier
Introduction Limited data exist on direct-acting oral anticoagulants in morbidly obese
patients with venous thromboembolism (VTE). We compared clinical and health/economic …
patients with venous thromboembolism (VTE). We compared clinical and health/economic …
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