Hypothalamic DNA methylation in rats with dihydrotestosterone‐induced polycystic ovary syndrome: effects of low‐frequency electro‐acupuncture

P Cui, T Ma, A Tamadon, S Han, B Li… - Experimental …, 2018 - Wiley Online Library
New Findings What is the central question of this study? What is the role of hypothalamic
DNA methylation in the development of polycystic ovary syndrome (PCOS) and the …

Low-frequency electro-acupuncture and physical exercise improve metabolic disturbances and modulate gene expression in adipose tissue in rats with …

L Manneras, IH Jonsdottir, A Holmang, M Lonn… - …, 2008 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder
associated with ovulatory dysfunction, hyperandrogenism, abdominal obesity, and insulin …

[HTML][HTML] Hypothalamic neuroendocrine functions in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency electro-acupuncture

Y Feng, J Johansson, R Shao, L Mannerås… - PLoS …, 2009 - journals.plos.org
Adult female rats continuously exposed to androgens from prepuberty have reproductive
and metabolic features of polycystic ovary syndrome (PCOS). We investigated whether such …

Electrical and manual acupuncture stimulation affect oestrous cyclicity and neuroendocrine function in an 5α‐dihydrotestosterone‐induced rat polycystic ovary …

Y Feng, J Johansson, R Shao, LM Holm… - Experimental …, 2012 - Wiley Online Library
Both low‐frequency electro‐acupuncture (EA) and manual acupuncture improve menstrual
frequency and decrease circulating androgens in women with polycystic ovary syndrome …

DNA methylation associated with polycystic ovary syndrome: a systematic review

AG Miranda, MM Seneda, LR Faustino - Archives of Gynecology and …, 2024 - Springer
Purpose Polycystic ovary syndrome (PCOS) is an endocrine metabolic disease that affects
women of reproductive age and is one of the main causes of anovulatory infertility. However …

[HTML][HTML] DNA methylation in polycystic ovary syndrome: emerging evidence and challenges

YN Liu, Y Qin, B Wu, H Peng, M Li, H Luo… - Reproductive Toxicology, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) is a disease related to reproductive endocrine
abnormalities in women of reproductive age, often accompanied by metabolic diseases …

DNA Hypomethylation–Mediated Transcription Dysregulation Participates in Pathogenesis of Polycystic Ovary Syndrome

P Cao, H Li, P Wang, X Zhang, Y Guo, K Zhao… - The American Journal of …, 2024 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly heterogeneous and genetically complex
endocrine disorder. Although the etiology remains mostly elusive, growing evidence …

[HTML][HTML] DNA methylation affects cell proliferation, cortisol secretion and steroidogenic gene expression in human adrenocortical NCI-H295R cells

J Liu, XD Li, A Vaheri… - Journal of molecular …, 2004 - jme.bioscientifica.com
Aberrant DNA methylation may be involved in human adrenocortical tumorigenesis, which is
often accompanied by abnormal hormone production. In this study, we aimed to clarify the …

Electroacupuncture stimulates hypothalamic aromatization

H Zhao, ZZ Tian, BY Chen - Brain Research, 2005 - Elsevier
We have previously reported that the repeated electroacupuncture (EA) stimulation
significantly increased the concentrations of circulating estradiol and restored the depressed …

Acupuncture does not ameliorate metabolic disturbances in the P450 aromatase inhibitor‐induced rat model of polycystic ovary syndrome

M Maliqueo, A Benrick, RR Marcondes… - Experimental …, 2017 - Wiley Online Library
New Findings What is the central question of this study? The effectiveness of low‐frequency
electroacupuncture in the treatment of metabolic disorders associated with polycystic ovary …