The fact that a debate concerning the unexpectedly high prevalence of normokalaemic
primary aldosteronism (PAL) attracted a large audience at the 2002 Scientific Meeting of the …

The identification of familial forms of primary aldosteronism (PAL) has led to its detection in
relatives of affected patients not suspected previously of having PAL. Many are …

Primary aldosteronism (PAL) has been traditionally regarded as a rare cause of
hypertension and not worth looking for in the absence of hypokalemia. However, the …

Of 93 patients with primary aldosteronism seen during a 20 year period, 52 had an
aldosterone‐producing adenoma (APA) removed (five more await surgery), 14 had bilateral …

Use of the random aldosterone-to-renin ratio (ARR) as a reliable marker of inappropriate
aldosterone activity has led to primary aldosteronism (PA) being increasingly diagnosed in …

Primary aldosteronism (PA) is the most common form of secondary hypertension, with a
prevalence of 5–10% among patients with hypertension. PA is mainly classified into two …

Wider application of the aldosterone/plasma renin activity ratio among hypertensives has
facilitated the detection of primary aldosteronism at earlier stages of evolution (with most …

Primary aldosteronism is commonly regarded as largely sporadic, but both germline and
somatic mutations are increasingly recognized as underlying the condition. Three germline …

The basic clinical pathophysiology of primary aldosteronism (PAL) was described by Conn
in terms of autonomous production of aldosterone, secondary suppression of renin and …

Primary aldosteronism is a common cause of endocrine hypertension. It results from the
excess production of aldosterone by the adrenal cortex and is related to increased morbidity …