Importance Patients with cancer who use statins appear to have a substantially better
survival than nonusers in observational studies. However, this inverse association between …

Background A reduction in the availability of cholesterol may limit the cellular proliferation
required for cancer growth and metastasis. We tested the hypothesis that statin use begun …

Background Previous studies have examined the effect of statin use on the mortality in
cancer patients, but the results are inconsistent. A meta-analysis was performed to assess …

Statins have been implicated in the regulation of cell proliferation, apoptosis and tumor
progression in cancer patients and statin use at the time of cancer diagnosis has been …

Purpose Several preclinical studies suggested a role for 3-hydroxy-3-methylglutaryl-
coenzyme A reductase inhibitors (statins) in the treatment of cancer. The objective of this …

Background: This study aims to investigate the association between statin use and all-
cancer survival in a prospective cohort of postmenopausal women, using data from the …

This is a comment on" Statin use and reduced cancer-related mortality." N Engl J Med. 2013
Feb 7; 368 (6): 574. This is a comment on" Statin use and reduced cancer-related mortality." …

PURPOSE: Although the short-term safety and tolerability of statins has been well
established, their potential carcinogenicity in the long term is still debated. The goal of this …

Background Preclinical evidence suggests statins may have anti-tumor properties. Large
observational studies are also consistent with improved survival and cancer-specific …

Background Meta-analyses of trials of 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors
or statins for cardiovascular disease prevention have failed to show any statistically …