Materials and Methods High-molecular weight DNA was extracted from 15 mL of amniotic
fluid, using the Promega Wizard Genomic DNA Purification Kit (Madison, WI, USA). A …

Non-invasive prenatal testing (NIPT) using cell-free DNA can detect fetal chromosomal
anomalies with high clinical sensitivity and specificity. In approximately 0.1% of clinical …

We report a new case of 46, XX male syndrome that was detected following an anomalous
result by non‐invasive prenatal testing (NIPT) and a discrepancy between the fetal …

Objective To report secondary or additional findings arising from introduction of non‐
invasive prenatal testing (NIPT) for aneuploidy by whole genome sequencing as a clinical …

Objective The aim of this study is to report the experience of noninvasive prenatal DNA
testing using massively parallel sequencing in an accredited clinical laboratory. Methods …

Cell-free fetal DNA has received significant attention for the purposes of prenatal genetic
testing in the past decade. Fetal DNA testing is a new method and promising for many …

DECEMBER 2014 American Journal of Obstetrics & Gynecology 711 ajog. org Letters to the
Editors authors comment that discordant or discrepant results may be explained by human …

Objective To gather additional data on the ability to detect subchromosomal abnormalities of
various sizes in single fetal cells isolated from maternal blood, using low‐coverage shotgun …

Background To detect complex fetal subchromosomal abnormalities by noninvasive
prenatal testing (NIPT). Case presentation After routine prenatal serum screening, the …

Purpose Noninvasive prenatal screening (NIPS) for fetal aneuploidy via cell-free DNA has
been commercially available in the United States since 2011. In 2016, the American College …