Advances in the development of new biomarkers for Alzheimer's disease

TO Klyucherev, P Olszewski, AA Shalimova… - Translational …, 2022 - Springer
Alzheimer's disease (AD) is a complex, heterogeneous, progressive disease and is the most
common type of neurodegenerative dementia. The prevalence of AD is expected to increase …

Biomarkers for Alzheimer's disease early diagnosis

E Ausó, V Gómez-Vicente, G Esquiva - Journal of Personalized Medicine, 2020 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia, affecting the central
nervous system (CNS) through the accumulation of intraneuronal neurofibrillary tau tangles …

Alzheimer's disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers

LYL Chang, J Lowe, A Ardiles, J Lim, AC Grey… - Alzheimer's & …, 2014 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia with progressive
deterioration of memory and cognition. Complaints related to vision are common among AD …

The eye as a biomarker for Alzheimer's disease

JKH Lim, QX Li, Z He, AJ Vingrys, VHY Wong… - Frontiers in …, 2016 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder resulting in dementia
and eventual death. It is the leading cause of dementia and the number of cases are …

[HTML][HTML] Visual and ocular manifestations of Alzheimer's disease and their use as biomarkers for diagnosis and progression

FZ Javaid, J Brenton, L Guo, MF Cordeiro - Frontiers in neurology, 2016 - frontiersin.org
Alzheimer's disease (AD) is the most common form of dementia affecting the growing aging
population today, with prevalence expected to rise over the next 35 years. Clinically, patients …

Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward

J Alber, D Goldfarb, LI Thompson, E Arthur… - Alzheimer's & …, 2020 - Wiley Online Library
The last decade has seen a substantial increase in research focused on the identification,
development, and validation of diagnostic and prognostic retinal biomarkers for Alzheimer's …

The retina as a window or mirror of the brain changes detected in Alzheimer's disease: critical aspects to unravel

S Chiquita, AC Rodrigues-Neves, FI Baptista… - Molecular …, 2019 - Springer
Alzheimer's disease is the most frequent cause of dementia worldwide, representing a
global health challenge, with a massive impact on the quality of life of Alzheimer's disease …

Ocular biomarkers for early detection of Alzheimer's disease

S Frost, RN Martins… - Journal of Alzheimer's …, 2010 - content.iospress.com
Alzheimer's disease (AD) is the most common form of dementia and is clinically
characterized by a progressive decline in memory, learning, and executive functions, and …

Retinal pathology as biomarker for cognitive impairment and Alzheimer's disease

MK Ikram, CY Cheung, TY Wong… - Journal of Neurology …, 2012 - jnnp.bmj.com
Alzheimer's disease (AD) is the most common cause of dementia. Furthermore, over the last
few decades, there has been a shift towards identifying earlier stages of AD, which include …

Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis

C Czakó, T Kovács, Z Ungvari, A Csiszar… - Geroscience, 2020 - Springer
Cognitive impairment and dementia are major medical, social, and economic public health
issues worldwide with significant implications for life quality in older adults. The leading …