Risk factors and biomarkers of age-related macular degeneration

NG Lambert, H ElShelmani, MK Singh… - Progress in retinal and …, 2016 - Elsevier
A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

[HTML][HTML] Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration

E Kersten, CC Paun, RL Schellevis, CB Hoyng… - survey of …, 2018 - Elsevier
Biomarkers can help unravel mechanisms of disease and identify new targets for therapy.
They can also be useful in clinical practice for monitoring disease progression, evaluation of …

Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors

Y Chen, J Zeng, C Zhao, K Wang, E Trood… - Archives of …, 2011 - jamanetwork.com
Objectives To evaluate the independent and joint effects of genetic factors and
environmental variables on advanced forms of age-related macular degeneration (AMD) …

Risk factors for progression of age‐related macular degeneration

TJ Heesterbeek, L Lorés‐Motta… - Ophthalmic and …, 2020 - Wiley Online Library
Purpose Age‐related macular degeneration (AMD) is a degenerative disease of the macula,
often leading to progressive vision loss. The rate of disease progression can vary among …

Mechanisms of age‐related macular degeneration and therapeutic opportunities

M van Lookeren Campagne, J LeCouter… - The Journal of …, 2014 - Wiley Online Library
As the age of the population increases in many nations, age‐related degenerative diseases
pose significant socioeconomic challenges. One of the key degenerative diseases that …

[HTML][HTML] Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy

Y Deng, L Qiao, M Du, C Qu, L Wan, J Li, L Huang - Genes & diseases, 2022 - Elsevier
Age-related macular degeneration (AMD) is a complex eye disorder and is the leading
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …

Genetic studies of age-related macular degeneration: lessons, challenges, and opportunities for disease management

RR Priya, EY Chew, A Swaroop - Ophthalmology, 2012 - Elsevier
BACKGROUND: Age-related macular degeneration (AMD) is a common cause of visual
impairment in individuals> 55 years of age worldwide. The varying clinical phenotypes of …

Recent developments in age-related macular degeneration: a review

WM Al-Zamil, SA Yassin - Clinical interventions in aging, 2017 - Taylor & Francis
Background Visual impairment in elderly people is a considerable health problem that
significantly affects quality of life of millions worldwide. The magnitude of this issue is …

Pathophysiology of age-related macular degeneration: implications for treatment

J Garcia-Garcia, R Usategui-Martin, MR Sanabria… - Ophthalmic …, 2022 - karger.com
Age-related macular degeneration (AMD) is a complex, multifactorial, progressive retinal
disease that affects millions of people worldwide and has become the leading cause of …

[HTML][HTML] Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors

KL Pennington, MM DeAngelis - Eye and vision, 2016 - Springer
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
adults over 50 years old. Genetic, epidemiological, and molecular studies are beginning to …