Cell death is critical for the development and homeostasis of almost all multicellular
organisms. Moreover, its dysregulation leads to diverse disease states. Historically …

The discovery of regulated cell death presents tantalizing possibilities for gaining control
over the life–death decisions made by cells in disease. Although apoptosis has been the …

Programmed cell death (PCD) has been a major area of constantly growing interest over the
last three decades. Originally, apoptosis was considered the only mechanistic pathway for …

Cell death plays a critical role in organism development and the pathogenesis of diseases.
Necrosis is considered a non-programmed cell death in an extreme environment. Recent …

Cell death is a fundamental physiological process that occurs in all organisms and is crucial
to each organism's evolution, ability to maintain a stable internal environment, and the …

Cells may die from accidental cell death (ACD) or regulated cell death (RCD). ACD is a
biologically uncontrolled process, whereas RCD involves tightly structured signaling …

Cell death is an essential process in all living organisms and occurs through different
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …

Cell death supports morphogenesis during development and homeostasis after birth by
removing damaged or obsolete cells. It also curtails the spread of pathogens by eliminating …

Various forms of cell death have been identified over the last decades with each relying on a
different subset of proteins for the activation and execution of their respective pathway (s). In …

Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …