The use of prenatal ultrasound has proven efficacious for the prenatal diagnosis of
chromosomal abnormalities. The first sonographic sign of Down syndrome, the thickened …

Current indications for cytogenetic evaluation leave the majority of Down syndrome fetuses
undetected. Using advanced maternal age and low maternal serum alpha‐fetoprotein (AFP) …

Objective To evaluate the efficacy of the second‐trimester genetic sonogram for the
detection of Down syndrome and other chromosomal abnormalities in a community‐based …

Prenatal diagnosis performed by fetal ultrasound scan is now a routine part of antenatal care
in many countries. We have used our registry of congenital malformations to determine how …

The Genetic Sonogram is an ultrasound examination done on second trimester fetuses that
not only evaluates the fetus for structural malformations, but also searches for the …

Real‐time and color Doppler ultrasound were used to examine 103 second trimester fetuses
with abnormal chromosomes (trisomies 13, 18, 21 and sex aneuploidy= 86; other= 17) and …

There has been an increase in the use of fetal ultrasound in the first trimester over the last
few years. This paper will review the published literature on first trimester ultrasound …

There is extensive evidence that effective screening for major chromosomal abnormalities
can be provided in the first trimester of pregnancy. Prospective studies in a total of 200,868 …

Ultrasound evidence for aneuploidy may be found in almost every organ of the fetus and can
be used to modify the risk of aneuploidy. The diagnosis of these minor anomalies on second …

Introduction This study assessed the sensitivity of routine ultrasound examination for the
detection of abnormal chromosomes and structural malformations in fetuses in the second …