Nanowired human cardiac organoid transplantation enables highly efficient and effective recovery of infarcted hearts
Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
Nanowires and electrical stimulation synergistically improve functions of hiPSC cardiac spheroids
The advancement of human induced pluripotent stem-cell-derived cardiomyocyte (hiPSC-
CM) technology has shown promising potential to provide a patient-specific, regenerative …
CM) technology has shown promising potential to provide a patient-specific, regenerative …
[HTML][HTML] Human pluripotent stem cell-derived cardiac tissue-like constructs for repairing the infarcted myocardium
High-purity cardiomyocytes (CMs) derived from human induced pluripotent stem cells
(hiPSCs) are promising for drug development and myocardial regeneration. However, most …
(hiPSCs) are promising for drug development and myocardial regeneration. However, most …
Functional engineered human cardiac patches prepared from nature's platform improve heart function after acute myocardial infarction
Q Wang, H Yang, A Bai, W Jiang, X Li, X Wang, Y Mao… - Biomaterials, 2016 - Elsevier
With the advent of induced pluripotent stem cells and directed differentiation techniques, it is
now feasible to derive individual-specific cardiac cells for human heart tissue engineering …
now feasible to derive individual-specific cardiac cells for human heart tissue engineering …
[HTML][HTML] Engineering the heart: evaluation of conductive nanomaterials for improving implant integration and cardiac function
Recently, carbon nanotubes together with other types of conductive materials have been
used to enhance the viability and function of cardiomyocytes in vitro. Here we demonstrated …
used to enhance the viability and function of cardiomyocytes in vitro. Here we demonstrated …
Silicon nanowire-induced maturation of cardiomyocytes derived from human induced pluripotent stem cells
The current inability to derive mature cardiomyocytes from human pluripotent stem cells has
been the limiting step for transitioning this powerful technology into clinical therapies. To …
been the limiting step for transitioning this powerful technology into clinical therapies. To …
Challenges and opportunities for the next generation of cardiovascular tissue engineering
Engineered cardiac tissues derived from human induced pluripotent stem cells offer unique
opportunities for patient-specific disease modeling, drug discovery and cardiac repair. Since …
opportunities for patient-specific disease modeling, drug discovery and cardiac repair. Since …
[HTML][HTML] Aligned nanofiber scaffolds improve functionality of cardiomyocytes differentiated from human induced pluripotent stem cell-derived cardiac progenitor cells
M Ding, H Andersson, S Martinsson, A Sabirsh… - Scientific reports, 2020 - nature.com
Cardiac progenitor cells (CPCs), capable of differentiating into multiple cardiac cell types
including cardiomyocytes (CMs), endothelial cells, and smooth muscle cells, are promising …
including cardiomyocytes (CMs), endothelial cells, and smooth muscle cells, are promising …
Transplanted microvessels improve pluripotent stem cell–derived cardiomyocyte engraftment and cardiac function after infarction in rats
X Sun, J Wu, B Qiang, R Romagnuolo… - Science translational …, 2020 - science.org
Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) offer an
unprecedented opportunity to remuscularize infarcted human hearts. However, studies have …
unprecedented opportunity to remuscularize infarcted human hearts. However, studies have …
[HTML][HTML] Cardiac repair in a porcine model of acute myocardial infarction with human induced pluripotent stem cell-derived cardiovascular cells
L Ye, YH Chang, Q Xiong, P Zhang, L Zhang… - Cell stem cell, 2014 - cell.com
Human induced pluripotent stem cells (hiPSCs) hold promise for myocardial repair following
injury, but preclinical studies in large animal models are required to determine optimal cell …
injury, but preclinical studies in large animal models are required to determine optimal cell …