Reactive oxygen species (ROS) act as signaling molecules that control physiological
processes, including cell adaptation to stress. Redox signaling via ROS has quite recently …

Background: Disruption of redox signaling is a common pathophysiological mechanism
observed in several diseases. In hypertension, oxidative stress, resulted either from …

Hypertension is a major cardiovascular risk factor. Of the many processes involved in the
pathophysiology of hypertension, vascular damage due to oxidative stress (excess …

A link between oxidative stress and hypertension has been firmly established in multiple
animal models of hypertension but remains elusive in humans. While initial studies focused …

Many factors have been implicated in the pathophysiology of hypertension such as
upregulation of the renin-angiotensin-aldosterone system, activation of the sympathetic …

Significance: Reactive oxygen species (ROS) are signaling molecules that are important in
physiological processes, including host defense, aging, and cellular homeostasis. Increased …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a key role in the
regulation of the physiological and pathological signaling within the vasculature. In …

Metabolism of oxygen by cells generates potentially deleterious reactive oxygen species
(ROS). Under normal conditions the rate and magnitude of oxidant formation is balanced by …

THIS FORUM ISSUE of Antioxidants & Redox Signaling highlights the role of reactive
oxygen species in hypertension. Although the association between free radicals and …

Reactive oxygen species (ROS) are products of normal cellular metabolism and derive from
various sources in different cellular compartments. Oxidative stress resultant from imbalance …