Background Asthma is a prevalent in ammatory lungs disease which poses a substantial
global health and economic burden. Abnormal glucose metabolism in asthmatic patients …

Glycolysis is a process that rapidly converts glucose to lactate to produce adenosine
triphosphate (ATP) under anaerobic conditions and occurs in all eukaryotic and prokaryotic …

Background Emerging studies suggest that enhanced glycolysis accompanies inflammatory
responses. Virtually nothing is known about the relevance of glycolysis in patients with …

Allergic asthma development and pathogenesis are influenced by airway epithelial cells in
response to allergens. Heme oxygenase‐1 (HO‐1), an inducible enzyme responsible for the …

Introduction: Despite the growing evidence of the critical role of metabolism in homeostasis
and chronic disease, there are few studies of its contribution to asthma pathogenesis. These …

The soluble epoxide hydrolase (sEH) has recently been demonstrated as a novel
therapeutic target for treating inflammation, Rationale: including pulmonary inflammation …

Rationale: Persistent activation of nuclear factor-κB has been associated with the
development of asthma. Glycogen synthase kinase-3β is known to regulate the activity of …

Early on-set allergic obese asthma is an important global clinical problem due to the
mounting number of patients and their disease severity that is poorly controlled with …

The aim of this study was to investigate whether the heme oxygenase (HO) pathway could
modulate proliferation of airway smooth muscle (ASM) and the mechanism (s) involved in …

Heme oxygenase-1 (HO-1) is not only a rate-limiting enzyme in heme metabolism but is also
regarded as a protective protein with an immunoregulation role in asthmatic airway …