[引用][C] Massive apixaban overdose-a comparison of three cases

J Ilicki, J Höjer, T Djärv - The American journal of …, 2018 - pubmed.ncbi.nlm.nih.gov
Massive apixaban overdose - A comparison of three cases Massive apixaban overdose - A
comparison of three cases Am J Emerg Med. 2018 May;36(5):891-893. doi: 10.1016/j.ajem.2017.09.035 …

The X factor: lack of bleeding after an acute apixaban overdose

SM Leikin, H Patel, KL Welker, JB Leikin - The American journal of …, 2017 - Elsevier
We present an acute apixaban overdose without reported coingestants; it is the first such
case report associated with multiple serum drug levels to assist in determining overdose …

Massive apixaban overdose confirmed with blood concentrations and managed without bleeding: A single case report

E Harmouche, P Stueve… - Journal of Pharmacy …, 2024 - journals.sagepub.com
Background: Acute overdoses of apixaban, and other direct oral anticoagulants are
relatively uncommon. The number of direct oral anticoagulants prescriptions in the United …

Anti-Xa activity in apixaban overdose: a case report

J Barton, A Wong, A Graudins - Clinical Toxicology, 2016 - Taylor & Francis
Introduction: Apixaban is a novel oral anticoagulation agent that exerts its effect through
direct factor Xa inhibition. We present a case of multi-drug overdose including apixaban with …

Coagulation assays in a case of apixaban overdose

DS Guadarrama, SM DeMarinis… - Blood Coagulation & …, 2018 - journals.lww.com
Intentional overdose of apixaban is rare and minimal data exist regarding the usefulness of
routinely available laboratory tests to predict drug levels. A 50-year-old man was admitted …

An observational study of the factor Xa inhibitors rivaroxaban and apixaban as reported to eight poison centers

HA Spiller, JB Mowry, A Aleguas Jr, JRK Griffith… - Annals of emergency …, 2016 - Elsevier
Study objective Rivaroxaban and apixaban are part of a new group of oral anticoagulants
targeting factor Xa and approved by the Food and Drug Administration in 2011 and 2012 …

Self‐poisoning with 60 tablets of Apixaban, a pharmacokinetics case report

B Franck, S Dulaurent, S El Balkhi… - British journal of …, 2019 - Wiley Online Library
A 67‐year‐old man was admitted to the emergency department about 5 h after deliberate
self‐poisoning with 300 mg of Apixaban. The clinical examination did not show any organ …

Accidental apixaban intoxication in a 23-month-old child: a case report

M Launay, Y Nasser, I Maubert, AC Chaux… - BMC pediatrics, 2020 - Springer
Background Direct oral anticoagulants, such as apixaban, are increasingly used in everyday
practice in order to treat or prevent thromboembolic diseases. To date, there is no available …

Drug-induced thrombocytopenia after anticoagulation with rivaroxaban

MK Pop, F Farokhi, L Iduna - The American journal of emergency medicine, 2018 - Elsevier
A 66-year-old man presented to the emergency department with complaints of dark-colored
stool and rash developing over the last couple of days. The patient was started on …

Administration of andexanet alfa for traumatic intracranial hemorrhage in the setting of massive apixaban overdose: A case report

D Jenniches, AF Kerns, J DelBianco… - American Journal of …, 2023 - academic.oup.com
Purpose Apixaban is a direct-acting oral anticoagulant that selectively inhibits factor Xa.
Reversal strategies utilized to treat factor Xa inhibitor–associated bleeding include …