Lung deflation and cardiovascular structure and function in chronic obstructive pulmonary disease. A randomized controlled trial
IS Stone, NC Barnes, WY James… - American journal of …, 2016 - atsjournals.org
Rationale: Patients with chronic obstructive pulmonary disease develop increased
cardiovascular morbidity with structural alterations. Objectives: To investigate through a …
cardiovascular morbidity with structural alterations. Objectives: To investigate through a …
[HTML][HTML] Lung deflation and oxygen pulse in COPD: results from the NETT randomized trial
BACKGROUND: In COPD patients, hyperinflation impairs cardiac function. We examined
whether lung deflation improves oxygen pulse, a surrogate marker of stroke volume …
whether lung deflation improves oxygen pulse, a surrogate marker of stroke volume …
Effect of indacaterol on lung deflation improves cardiac performance in hyperinflated COPD patients: an interventional, randomized, double-blind clinical trial
P Santus, D Radovanovic, S Di Marco… - … journal of chronic …, 2015 - Taylor & Francis
Background COPD is often associated with cardiovascular comorbidity. Treatment
guidelines recommend therapy with bronchodilators as first choice. We investigated the …
guidelines recommend therapy with bronchodilators as first choice. We investigated the …
Lung hyperinflation in chronic obstructive pulmonary disease: mechanisms, clinical implications and treatment
Lung hyperinflation is highly prevalent in patients with chronic obstructive pulmonary
disease and occurs across the continuum of the disease. A growing body of evidence …
disease and occurs across the continuum of the disease. A growing body of evidence …
Effect of lung deflation with indacaterol plus glycopyrronium on ventricular filling in patients with hyperinflation and COPD (CLAIM): a double-blind, randomised …
JM Hohlfeld, J Vogel-Claussen, H Biller… - The Lancet …, 2018 - thelancet.com
Background Pulmonary hyperinflation in chronic obstructive pulmonary disease (COPD) is
associated with reduced biventricular end-diastolic volumes and increased morbidity and …
associated with reduced biventricular end-diastolic volumes and increased morbidity and …
Why does the lung hyperinflate?
GT Ferguson - Proceedings of the American Thoracic Society, 2006 - atsjournals.org
Patients with chronic obstructive pulmonary disease (COPD) often have some degree of
hyperinflation of the lungs. Hyperinflated lungs can produce significant detrimental effects on …
hyperinflation of the lungs. Hyperinflated lungs can produce significant detrimental effects on …
Arterial vascular pruning, right ventricular size, and clinical outcomes in chronic obstructive pulmonary disease. A longitudinal observational study
GR Washko, P Nardelli, SY Ash… - American journal of …, 2019 - atsjournals.org
Rationale: Cor pulmonale (right ventricular [RV] dilation) and cor pulmonale parvus (RV
shrinkage) are both described in chronic obstructive pulmonary disease (COPD). The …
shrinkage) are both described in chronic obstructive pulmonary disease (COPD). The …
The connection between chronic obstructive pulmonary disease symptoms and hyperinflation and its impact on exercise and function
CB Cooper - The American journal of medicine, 2006 - Elsevier
Forced expiratory volume in 1 second (FEV1) has served as an important diagnostic
measurement of chronic obstructive pulmonary disease (COPD) but has not been found to …
measurement of chronic obstructive pulmonary disease (COPD) but has not been found to …
New physiological insights into dyspnea and exercise intolerance in chronic obstructive pulmonary disease patients
P Laveneziana, JA Guenette, KA Webb… - Expert review of …, 2012 - Taylor & Francis
Dyspnea and reduced exercise tolerance are common consequences of chronic obstructive
pulmonary disease (COPD) and contribute importantly to poor perceived health status …
pulmonary disease (COPD) and contribute importantly to poor perceived health status …
Pathogenesis of hyperinflation in chronic obstructive pulmonary disease
P Gagnon, JA Guenette, D Langer… - … journal of chronic …, 2014 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable lung disease
characterized by airflow limitation that is not fully reversible. In a significant proportion of …
characterized by airflow limitation that is not fully reversible. In a significant proportion of …