Glucocorticoids exert pleiotropic effects on all tissues to regulate cellular and metabolic
homeostasis. Synthetic forms are used therapeutically in a wide range of conditions for their …

Glucocorticoids are a vital class of endogenous steroid hormones that regulate essential
biological processes including growth, development, metabolism, behavior and apoptosis …

Glucocorticoids and their synthetic derivatives are among the most widely prescribed class
of drug in the world today. The ability of both natural and synthetic glucocorticoids to act on …

Glucocorticoids are well known for their potent anti-inflammatory and immune-suppressive
actions. Their clinical usefulness remains limited due to serious side effects that have …

Since their discovery in the 1940s, glucocorticoids remain one of the most widely prescribed
drugs in the world to treat inflammatory and autoimmune disorders, including arthritis …

Glucocorticoid hormones are essential for life, have a vital place in the treatment of
inflammatory and autoimmune diseases and are increasingly implicated in the pathogenesis …

Synthetic glucocorticoids are among the most effective anti-inflammatory drugs available.
The activity of this drug class is mediated by the glucocorticoid receptor, a nuclear steroid …

Glucocorticoids are steroid hormones that have pleiotropic effects on development,
metabolism, cognitive function and other aspects of physiology. Since the demonstration …

Glucocorticoids have a broad array of life-sustaining functions, such as for the maintenance
of the basal-and stress-related organ homeostasis. They are also frequently used as …

It has become apparent in recent years that the glucocorticoid receptor is not a simple on/off
switch, but instead orchestrates subtle and complex interactions between large numbers of …