Phage therapy in Germany—update 2023

C Willy, JJ Bugert, AY Classen, L Deng, A Düchting… - Viruses, 2023 - mdpi.com
Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally
and in Germany. Here, we provide an overview of the current situation (2023) of applied …

A wake-up call: we need phage therapy now

K Moelling, F Broecker, C Willy - Viruses, 2018 - mdpi.com
The rise of multidrug-resistant bacteria has resulted in an increased interest in phage
therapy, which historically preceded antibiotic treatment against bacterial infections. To date …

Current updates from the long-standing phage research centers in Georgia, Poland, and Russia

R Międzybrodzki, N Hoyle, F Zhvaniya… - Bacteriophages: biology …, 2021 - Springer
Abstract The George Eliava Institute of Bacteriophages, Microbiology and Virology (IBMV) in
Tbilisi, Georgia; the Hirszfeld Institute of Immunology and Experimental Therapy in Wroclaw …

Bacteriophage Therapy for Difficult-to-Treat Infections: The Implementation of a Multidisciplinary Phage Task Force (The PHAGEFORCE Study Protocol)

J Onsea, S Uyttebroek, B Chen, J Wagemans, C Lood… - Viruses, 2021 - mdpi.com
In times where only a few novel antibiotics are to be expected, antimicrobial resistance
remains an expanding global health threat. In case of chronic infections caused by therapy …

Bacteriophage therapy: clinical trials and regulatory hurdles

LL Furfaro, MS Payne, BJ Chang - Frontiers in cellular and infection …, 2018 - frontiersin.org
Increasing reports of antimicrobial resistance and limited new antibiotic discoveries and
development have fuelled innovation in other research fields and led to a revitalization of …

Phage therapy: delivering on the promise

DR Harper, J Anderson, MC Enright - Therapeutic delivery, 2011 - Taylor & Francis
Bacteriophages are viruses that infect and, in many cases, destroy their bacterial targets.
Within a few years of their initial discovery they were being investigated as therapeutic …

Current clinical landscape and global potential of bacteriophage therapy

NM Hitchcock, D Devequi Gomes Nunes, J Shiach… - Viruses, 2023 - mdpi.com
In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …

A thorough synthesis of phage therapy unit activity in Poland—its history, milestones and international recognition

M Żaczek, A Górski, B Weber-Dąbrowska, S Letkiewicz… - Viruses, 2022 - mdpi.com
The year 2020 marked 15 years of the Phage Therapy Unit in Poland, the inception of which
took place just one year after Poland's accession to the European Union (2004). At first sight …

The future of clinical phage therapy in the United Kingdom

JD Jones, C Trippett, M Suleman, MRJ Clokie, JR Clark - Viruses, 2023 - mdpi.com
Bacteriophage (phage) therapy is a promising alternative antimicrobial strategy with the
potential to transform the way bacterial infections are treated. In the United Kingdom, phages …

Clinical application of bacteriophages in Europe

JP Pirnay, D De Vos, G Verbeken - Microbiology Australia, 2019 - CSIRO Publishing
Bacteriophages could help address the antibiotic resistance crisis that impacts health
systems all over the world. In 2011, the European Commission formally confirmed that …