Chemotherapy-induced neuropathic pain is a serious clinical problem and one of the major
side effects in cancer treatment. The endocannabinoid system (ECS) plays a crucial role in …

There is a scarcity of drugs to either prevent or properly manage chemotherapy‐induced
neuropathic pain (CINP). Cannabis or cannabinoids have been reported to improve pain …

Chemotherapy-induced neuropathic pain is a distressing and commonly occurring side
effect of many commonly used chemotherapeutic agents, which in some cases may prevent …

The analgesic effects of cannabinoids are well documented, but these are often limited by
psychoactive side-effects. Recent studies indicate that the endocannabinoid system is …

Chronic pain states are highly prevalent and yet poorly controlled by currently available
analgesics, representing an enormous clinical, societal, and economic burden. Existing pain …

Oxaliplatin-induced neurotoxicity is expressed as a dose-limiting peripheral sensory
neuropathy (PSN). Cannabinoid substances have been investigated for the analgesic effect …

Clinical use of antineoplastic drugs is associated with the development of numerous
adverse effects that many patients find intolerable, including peripheral neuropathy …

The analgesic effects of cannabinoid ligands, mediated by CB1 receptors are well
established. However, the side-effect profile of CB1 receptor ligands has necessitated the …

The research of new therapeutic strategies for neuropathic pain represents a major current
priority. Important drawbacks to advance in the development of these therapies are the …

A great need exists for the development of new medications to treat pain resulting from
various disease states and types of injury. Given that the endogenous cannabinoid (that is …