Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …

Mitochondria play a vital role in the nervous system, as they are responsible for generating
energy in the form of ATP and regulating cellular processes such as calcium (Ca 2+) …

Mitochondria are the power engine generating biochemical energy in the cell. Mitochondrial
dysfunction and bioenergy deficiency is closely linked to the pathogenesis of …

Mitochondrial dysfunction has been reported in a wide array of neurological disorders
ranging from neuromuscular to neurodegenerative diseases. Recent studies on …

Neurodegenerative diseases (NDD) are incurable and the most prevalent cognitive and
motor disorders of elderly. Mitochondria are essential for a wide range of cellular processes …

Neurodegenerative diseases are incurable and inexorably progressive conditions that affect
the central nervous system and result in a selective pattern of neuronal death. Parkinson's …

Mitochondria play a central role in a plethora of processes related to the maintenance of
cellular homeostasis and genomic integrity. They contribute to preserving the optimal …

The mitochondrion is the most important organelle in determining continued cell survival
and cell death. Mitochondrial dysfunction leads to many human maladies, including …

Mitochondria are one of the essential cellular organelles. Apart from being considered as
the powerhouse of the cell, mitochondria have been widely known to regulate redox …

In recent years, multiple disciplines have focused on mitochondrial biology and contributed
to understanding its relevance towards adult-onset neurodegenerative disorders. These are …