Evaluating Burkholderia pseudomallei Bip proteins as vaccines and Bip antibodies as detection agents

C Druar, F Yu, JL Barnes, RT Okinaka… - FEMS Immunology & …, 2008 - academic.oup.com
Burkholderia pseudomallei is a biothreat agent and an important natural pathogen, causing
melioidosis in humans and animals. A type III secretion system (TTSS-3) has been shown to …

BPSS1504, a Cluster 1 Type VI Secretion Gene, Is Involved in Intracellular Survival and Virulence of Burkholderia pseudomallei

V Hopf, A Göhler, K Eske-Pogodda, A Bast… - Infection and …, 2014 - Am Soc Microbiol
Burkholderia pseudomallei is a Gram-negative rod and the causative agent of melioidosis,
an emerging infectious disease of tropical and subtropical areas worldwide. B. pseudomallei …

Human Immune Responses to Burkholderia pseudomallei Characterized by Protein Microarray Analysis

D Suwannasaen, J Mahawantung… - The Journal of …, 2011 - academic.oup.com
Background. We aimed to determine the antibody and T cell responses to Burkholderia
pseudomallei of humans to select candidate vaccine antigens. Methods. For antibody …

A Live Experimental Vaccine against Burkholderia pseudomallei Elicits CD4+ T Cell–Mediated Immunity, Priming T Cells Specific for 2 Type III Secretion System …

A Haque, K Chu, A Easton, MP Stevens… - The Journal of …, 2006 - academic.oup.com
Burkholderia pseudomallei is the etiological agent of melioidosis, a serious human disease
for which no vaccine is available. Immunization of susceptible BALB/c mice with the live …

Functional Characterizations of Effector Protein BipC, a Type III Secretion System Protein, in Burkholderia pseudomallei Pathogenesis

WT Kang, KM Vellasamy, EG Chua… - The Journal of …, 2015 - academic.oup.com
Objectives. The bsa locus of Burkholderia pseudomallei encodes several proteins that are
components of the type III secretion system (TTSS). BipC was postulated as one of the TTSS …

Burkholderia thailandensis as a Model System for the Study of the Virulence-Associated Type III Secretion System of Burkholderia pseudomallei

A Haraga, TE West, MJ Brittnacher… - Infection and …, 2008 - Am Soc Microbiol
Burkholderia pseudomallei is a bacterial pathogen that causes a broad spectrum of clinical
symptoms collectively known as melioidosis. Since it can be acquired by inhalation and is …

Comparative assessment of the intracellular survival of the Burkholderia pseudomallei bopC mutant

V Srinon, S Muangman, N Imyaem… - Journal of …, 2013 - Springer
Burkholderia pseudomallei, the causative agent of melioidosis, is a Gram-negative
saprophytic bacterium capable of surviving within phagocytic cells. To assess the role of …

Identification and Discrimination of Burkholderia pseudomallei, B. mallei, and B. thailandensis by Real-Time PCR Targeting Type III Secretion System Genes

FM Thibault, E Valade, DR Vidal - Journal of clinical microbiology, 2004 - Am Soc Microbiol
Burkholderia pseudomallei and B. mallei are two highly pathogenic bacteria, responsible for
melioidosis and glanders, respectively. The two are closely related and can also be …

[HTML][HTML] Rapid and Sensitive Multiplex Detection of Burkholderia pseudomallei-Specific Antibodies in Melioidosis Patients Based on a Protein Microarray Approach

C Kohler, SJ Dunachie, E Müller, A Kohler… - PLoS neglected …, 2016 - journals.plos.org
Background The environmental bacterium Burkholderia pseudomallei causes the infectious
disease melioidosis with a high case-fatality rate in tropical and subtropical regions. Direct …

Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis

MP Stevens, A Haque, T Atkins, J Hill… - …, 2004 - microbiologyresearch.org
Melioidosis is a severe infectious disease of animals and humans caused by the Gram-
negative intracellular pathogen Burkholderia pseudomallei. An Inv/Mxi-Spa-like type III …