Outlining the skin-homing and circulating CLA+NK cells in patients with severe atopic dermatitis
JF de Lima, FME Teixeira, YÁL Ramos… - Scientific Reports, 2024 - nature.com
Atopic dermatitis (AD) is a complex, multifactorial skin disease, characterized by pruritus and
predominant Th2 inflammation. Innate immune cells may play a role in AD development and …
predominant Th2 inflammation. Innate immune cells may play a role in AD development and …
Naïve CD4+ T cells from patients with atopic dermatitis show an aberrant maturation towards IL‐4‐producing skin‐homing CLA+ cells
T Jung, R Moessner, C Neumann - Experimental dermatology, 2003 - Wiley Online Library
Overproduction of interleukin‐4 (IL‐4) has been reported in lesional and in peripheral T cells
from patients with atopic dermatitis (AD). It is not clear whether the development of IL‐4 …
from patients with atopic dermatitis (AD). It is not clear whether the development of IL‐4 …
Circulating CLA+ T cells in atopic dermatitis and their possible role as peripheral biomarkers
T Czarnowicki, LF Santamaria‐Babí… - Allergy, 2017 - Wiley Online Library
Cutaneous lymphocyte‐associated antigen (CLA+) T cells are specialized for skin homing
and represent the main T‐cell population in atopic dermatitis (AD) lesions. CLA+ is …
and represent the main T‐cell population in atopic dermatitis (AD) lesions. CLA+ is …
CLA+ memory T cells in atopic dermatitis: CLA+ T cells and atopic dermatitis
L Sans-de San Nicolás, T Czarnowicki… - Allergy. 2024 Jan; 79 …, 2024 - repositori.upf.edu
Circulating skin-homing cutaneous lymphocyte-associated antigen (CLA)+ T cells constitute
a small subset of human memory T cells involved in several aspects of atopic dermatitis …
a small subset of human memory T cells involved in several aspects of atopic dermatitis …
Skin homing (cutaneous lymphocyte-associated antigen-positive) CD8+ T cells respond to superantigen and contribute to eosinophilia and IgE production in atopic …
M Akdis, HU Simon, L Weigl, O Kreyden… - The Journal of …, 1999 - journals.aai.org
In allergic inflammations of the skin, activation of CD4+ T cells was demonstrated to play an
important role; however, a minor role for CD8+ T cells is implied. In the present study, we …
important role; however, a minor role for CD8+ T cells is implied. In the present study, we …
Regulation of Allergic Inflammation by Skin–Homing T Cells in Allergic Eczema
Background: In allergic inflammations of the skin, the pivotal role of CD45RO+(memory/
effector) T cells expressing the cutaneous lymphocyte–associated antigen (CLA) was …
effector) T cells expressing the cutaneous lymphocyte–associated antigen (CLA) was …
The role of skin-homing T cells in extrinsic atopic dermatitis
Background: T cells that express Cutaneous Lymphocyte-Associated antigen (CLA) have
the potential of migrating to the skin, and are hypothesized to play a role in cutaneous atopic …
the potential of migrating to the skin, and are hypothesized to play a role in cutaneous atopic …
Different cytokine production and activation marker profiles in circulating cutaneous‐lymphocyte‐associated antigen+ T cells from patients with acute or chronic atopic …
Background Atopic dermatitis (AD) is an inflammatory skin disease whose lesions can have
two stages: acute and chronic. In skin biopsies a biphasic pattern of cytokine expression has …
two stages: acute and chronic. In skin biopsies a biphasic pattern of cytokine expression has …
CLA+ memory T cells in atopic dermatitis: CLA+ T cells and atopic dermatitis
LSS Nicolàs, T Czarnowicki, M Akdis, RM Pujol… - Allergy, 2024 - Wiley Online Library
Circulating skin‐homing cutaneous lymphocyte‐associated antigen (CLA)+ T cells constitute
a small subset of human memory T cells involved in several aspects of atopic dermatitis …
a small subset of human memory T cells involved in several aspects of atopic dermatitis …
Increased circulating skin‐homing cutaneous lymphocyte‐associated antigen (CLA)+ type 2 cytokine‐producing cells, and decreased CLA+ type 1 cytokine …
Y Teraki, T Hotta, T Shiohara - British Journal of Dermatology, 2000 - academic.oup.com
Background Skin‐homing T cells are characterized by expression of cutaneous lymphocyte‐
associated antigen (CLA). Few data are available on the frequency of circulating CLA+ …
associated antigen (CLA). Few data are available on the frequency of circulating CLA+ …
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