It is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with
Alzheimer's disease (AD). Recently, we showed that abnormal levels of Aβ42 in …

BACKGROUND: Important functional connections within the default mode network (DMN)
are disrupted in Alzheimer's disease (AD), likely from amyloid-beta (Aβ) plaque-associated …

There has been a dramatic increase in the number of studies using resting state functional
magnetic resonance imaging (rs-fMRI), a recent addition to imaging analysis techniques …

Alzheimer's disease (AD) has been associated with functional alterations in a distributed
network of brain regions linked to memory function, with a recent focus on the cortical …

Although beta-amyloid (Aβ) deposition is a characteristic feature of Alzheimer's disease
(AD), this pathology is commonly found in elderly normal controls (NC). The pattern of Aβ …

Although previous studies have emphasized the vulnerability of the default mode network
(DMN) in Alzheimer's disease (AD), little is known about the involvement of other functional …

Beta-amyloid (Aβ) deposition is one of the hallmarks of Alzheimer's disease (AD). However,
it is also present in some cognitively normal elderly adults and may represent a preclinical …

Objective: To investigate age-related default mode network (DMN) connectivity in a large
cognitively normal elderly cohort and in patients with Alzheimer disease (AD) compared with …

The link between brain amyloid-β (Aβ), metabolism, and dementia symptoms remains a
pressing question in Alzheimer's disease. Here, using positron emission tomography ([18F] …

The common and specific involvement of brain networks in clinical variants of Alzheimer's
disease (AD) is not well understood. We performed task-free (“resting-state”) functional …