Background Allergic rhinitis (AR) is a prevalent immune-related allergic disease, and
corticosteroid nasal sprays serve as the primary treatment for this patient population …

Allergic rhinitis (AR) is a type-I hypersensitivity disease mediated by immunoglobulin E (IgE).
Although antihistamines, glucocorticoids, leukotriene receptor antagonists, and other drugs …

Glucocorticoids are widely used for treating allergic rhinitis, but conventional intranasal
administration encounters unfavorable nasal cilia clearance and nasal mucosal barrier …

In this study, we suggest the development of nanoparticle loaded in situ gelling system
suitable for corticosteroid nasal delivery. We propose lipid/alginate nanoparticles (size …

To demonstrate safety of a developed intranasal dexamethasone-infused in situ gelling
formulation, quantification of a validated clinical biomarker indicative of cytotoxic potential …

Abstract Relapse in Allergic Rhinitis (AR) is triggered by various unclear mechanisms.
Xanthium strumarium L. as a traditional folk medicine can inhibit inflammatory responses …

Asthma is a common airway inflammatory disorder, characterized by increased infiltration of
leukocytes and bronchoconstriction. Dexamethasone (DEX) has been widely used in the …

In this study, we present the development of an innovative dry powder dexamethasone
(Dex) nasal delivery system comprising Dex-loaded lipid/alginate nanoparticles …

Atopic dermatitis (AD) is a chronic and recurrent inflammation disease associated with
immune dysfunction. The high level of reactive oxygen species (ROS) causes high oxidative …

Intranasal administration has been widely explored as a potential treatment for allergic
rhinitis, and improving intranasal penetration and retention of drugs is a challenging …