Designing melittin‐graphene hybrid complexes for enhanced antibacterial activity

X Lu, J Liu, L Gou, J Li, B Yuan… - Advanced healthcare …, 2019 - Wiley Online Library
Antimicrobial peptides (AMPs) promise a fundamental solution to the devastating threat of
drug‐resistant bacteria. However, drawbacks of AMPs (eg, poor cell membrane penetration …

Graphene oxide as antibacterial sensitizer: Mechanically disturbed cell membrane for enhanced poration efficiency of melittin

S Xiao, X Lu, L Gou, J Li, Y Ma, J Liu, K Yang, B Yuan - Carbon, 2019 - Elsevier
Natural antimicrobial peptides (AMPs) promise a fundamental solution to the devastating
threat of multidrug-resistant bacteria, while drawbacks such as limited antibacterial efficiency …

Synthetic peptide (DP1) functionalized graphene oxide: A biocompatible nanoformulation with broad-spectrum antibacterial and antibiofilm activity

S Joshi, J Chadha, K Harjai, G Verma, A Saini - FlatChem, 2024 - Elsevier
In the present scenario, clinical success of all existing antimicrobial regimes has been
severely challenged by bacterial infections and emergence of multidrug-resistant strains …

Antibacterial and antibiofouling activities of antimicrobial peptide-functionalized graphene–silver nanocomposites for the inhibition and disruption of Staphylococcus …

T Parandhaman, P Choudhary… - ACS Biomaterials …, 2021 - ACS Publications
Owing to the emergence of antibiotic-resistant strains, bacterial infection and biofilm
formation are growing concerns in healthcare management. Herein, we report an eco …

Novel cyclic undecapeptides immobilized on reduced graphene oxide surface for enhanced antibacterial properties

HN Farrag, ALT Zheng, S Sabidi, Y Wu, S Ikeno… - International Journal of …, 2024 - Springer
The incorporation of antimicrobial peptides (AMPs) in graphene-based materials is a
growing strategy to overcome the shortcomings presented by conventional antimicrobial …

Development of antibacterial peptides with efficient antibacterial activity, low toxicity, high membrane disruptive activity and a synergistic antibacterial effect

H Wang, M Niu, T Xue, L Ma, X Gu, G Wei… - Journal of Materials …, 2022 - pubs.rsc.org
The development of new antimicrobial drugs is urgently required to overcome bacterial
resistance which is a serious threat to human health. Antimicrobial peptides (AMPs) which …

[HTML][HTML] A molecular architectural design that promises potent antimicrobial activity against multidrug-resistant pathogens

B Yuan, J Liu, Z Deng, L Wei, W Li, Y Dou, Z Chen… - NPG Asia …, 2021 - nature.com
Addressing the devastating threat of drug-resistant pathogens requires the discovery of new
antibiotics with advanced action mechanisms and/or novel strategies for drug design …

Covalent functionalization of graphene sheets with different moieties and their effects on biological activities

M Assali, M Almasri, N Kittana… - ACS Biomaterials Science …, 2019 - ACS Publications
The ongoing spread of multi-drug-resistant bacteria over the past few decades necessitates
collateral efforts to develop new classes of antibacterial agents with different mechanisms of …

Emerging trends and future direction of graphene family of materials as potential antimicrobials: A critical review

SS Nasker, PM Ajayan, S Nayak - ACS Materials Letters, 2023 - ACS Publications
Graphene research has progressed at an unprecedented rate since 2004 when Novoselov
and Geim isolated and described a single sheet of graphene. In fact, the relentless progress …

De Novo Designed Hexadecapeptides Synergize Glycopeptide Antibiotics Vancomycin and Teicoplanin against Pathogenic Klebsiella pneumoniae via Disruption of …

P Zeng, C Xu, C Liu, J Liu, Q Cheng… - ACS Applied Bio …, 2020 - ACS Publications
Given the worldwide prevalence of pathogenic drug-resistant bacteria and the slow pace of
new antibacterial development, discovering new uses for approved drugs that are outside …