Type 2 diabetes is a risk factor for developing Alzheimer's disease (AD). The underlying
mechanism that links up the two conditions seems to be the de-sensitization of insulin …

Alzheimer's disease (AD) and type 2 diabetes (T2DM) are the two major health issues
affecting millions of elderly people worldwide, with major impacts in the patient's daily life …

Alzheimer's disease (AD) is the most common form of dementia affecting elderly people. AD
is a multifaceted pathology characterized by accumulation of extracellular neuritic plaques …

Alzheimer's disease (AD) is the main type of dementia and is a disease with a profound
socioeconomic burden due to the lack of effective treatment. In addition to genetics and …

Introduction• Insulin, IGF‐1 in the brain• Glucose metabolism and AD• The insulin and IGF‐1
system in AD• The insulin and oxidative stress in AD• The insulin and IGF‐1R system and τ …

Alterations of the insulin signaling cascade underlie cognitive decline and the development
of several neurodegenerative diseases. In recent years, a great interest has been put in …

Alzheimer's disease (AD) has characteristic neuropathological abnormalities including
regionalized neurodegeneration, neurofibrillary tangles, amyloid beta (Aβ) deposition …

Alzheimer disease (AD) is the most common form of dementia. Different pathogenic
processes have been studied that underlie characteristic changes of AD, including Aβ …

A link between Alzheimer's disease (AD) and metabolic disorders has been established,
with patients with type 2 diabetes at increased risk of developing AD and vice versa. The …

Alzheimer's disease (AD) and type 2 diabetes (T2D) major feature is insulin resistance.
Brain and peripheral insulin resistance lead to hyperglycemia, which contributes to the …