Chronic wounds occur as a consequence of a prolonged inflammatory phase during the
healing process, which precludes skin regeneration. Typical treatment for chronic wounds …

The formation of severe scars still represents the result of the closure process of extended
and deep skin wounds. To address this issue, different bioengineered skin substitutes have …

Tissue-engineered skin is a significant advance in the field of wound healing. It has mainly
been developed because of limitations associated with the use of autografts and allografts …

Skin as a mechanical barrier between the inner and outer environment of our body protects
us against infection and electrolyte loss. This organ consists of 3 layers: the epidermis …

Skin is the largest organ of human body, acting as a barrier with protective, immunologic and
sensorial functions. Its permanent exposure to the external environment can result in …

The fundamental skin role is to supply a supportive barrier to protect body against harmful
agents and injuries. Three layers of skin including epidermis, dermis and hypodermis form a …

As the largest organ in the human body, the skin has the function of maintaining balance
and protecting from external factors such as bacteria, chemicals, and temperature. If the …

Regenerative medicine and tissue engineering (TE) have experienced significant advances
in the development of in vitro engineered skin substitutes, either for replacement of lost …

Skin tissue engineering has attained several clinical milestones making remarkable
progress over the past decades. Skin is inhabited by a plethora of cells spatiotemporally …

The tissue engineering field has developed in response to the shortcomings related to the
replacement of the tissues lost to disease or trauma: donor tissue rejection, chronic …