[HTML][HTML] Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures

I Shaikh, A Ansari, G Ayachit, M Gandhi, P Sharma… - Oncotarget, 2019 - ncbi.nlm.nih.gov
Head and neck cancer is the sixth most common cancer worldwide, with tobacco as the
leading cause. However, it is increasing in non-tobacco users also, hence limiting our …

Differential effect of smoking on gene expression in head and neck cancer patients

AI Irimie, C Braicu, R Cojocneanu, L Magdo… - International journal of …, 2018 - mdpi.com
Smoking is a well-known behavior that has an important negative impact on human health,
and is considered to be a significant factor related to the development and progression of …

Genome-wide gene expression profiling of tongue squamous cell carcinoma by RNA-seq

HX Zhang, OS Liu, C Deng, Y He, YQ Feng… - Clinical Oral …, 2018 - Springer
Objective Tongue squamous cell carcinoma (TSCC) is significantly more malignant than
other type of oral squamous cell carcinoma (OSCC). In this study, we aimed to identify …

Drug targeting and biomarkers in head and neck cancers: insights from systems biology analyses

T Islam, R Rahman, E Gov, B Turanli… - Omics: a journal of …, 2018 - liebertpub.com
The head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers
in the world, but robust biomarkers and diagnostics are still not available. This study …

Integrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic …

L Wang, R Yang, Y Kong, J Zhou, Y Chen… - International Journal of …, 2024 - nature.com
Metabolic heterogeneity plays a central role in sustaining uncontrolled cancer cell
proliferation and shaping the tumor microenvironment (TME), which significantly …

Identification of potential biomarkers and survival analysis for head and neck squamous cell carcinoma using bioinformatics strategy: a study based on TCGA and …

Y Shen, J Liu, L Zhang, S Dong, J Zhang… - BioMed research …, 2019 - Wiley Online Library
The mechanism and gene markers of head and neck squamous cell carcinoma (HNSCC), a
common malignant tumor, have not yet been identified. The aim of this study was to identify …

Transcriptome analysis of tongue cancer based on high‑throughput sequencing

M Tang, W Dai, H Wu, X Xu, B Jiang… - Oncology …, 2020 - spandidos-publications.com
Tongue cancer is one of the most common types of cancer, but its molecular etiology and
pathogenesis remain unclear. The aim of the present study was to elucidate the …

[HTML][HTML] Comprehensive analysis of transcriptome data for identifying biomarkers and therapeutic targets in head and neck squamous cell carcinoma

Y Jin, X Qin - Annals of Translational Medicine, 2020 - ncbi.nlm.nih.gov
Background Head and neck squamous cell carcinoma (HNSCC) is one of the most common
malignancy worldwide. Accumulating evidences have highlighted the importance of …

Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: A prospective …

AP Zammit, R Sinha, CL Cooper, CFL Perry, IH Frazer… - PLoS …, 2018 - journals.plos.org
Oral cavity Squamous Cell Carcinoma (OCSCC) is a common form of head and neck cancer
throughout the developed and developing world. However, the etiology of OCSCC is still …

Analysis of the TCGA dataset reveals that subsites of laryngeal squamous cell carcinoma are molecularly distinct

A Sorgini, HAJ Kim, PYF Zeng, MH Shaikh, N Mundi… - Cancers, 2020 - mdpi.com
Simple Summary Squamous cell carcinomas from different parts of the larynx have distinct
presentations and prognoses, but the molecular basis for this discrepancy has yet to be …