Immune-mediated attenuation of influenza illness after infection: opportunities and challenges
Sterilising immunity that blocks infection for life, and thus prevents illness after infection, is
the ultimate goal for vaccines. Neither influenza infection nor vaccination provide sterilising …
the ultimate goal for vaccines. Neither influenza infection nor vaccination provide sterilising …
[HTML][HTML] The human antibody response to influenza A virus infection and vaccination
F Krammer - Nature Reviews Immunology, 2019 - nature.com
The adaptive immune response to influenza virus infection is multifaceted and complex,
involving antibody and cellular responses at both systemic and mucosal levels. Immune …
involving antibody and cellular responses at both systemic and mucosal levels. Immune …
Yearly influenza vaccinations: a double-edged sword?
R Bodewes, JHCM Kreijtz… - The Lancet infectious …, 2009 - thelancet.com
Yearly vaccination against seasonal influenza viruses is recommended for certain
individuals at high risk of complications associated with influenza. It has been recommended …
individuals at high risk of complications associated with influenza. It has been recommended …
Universal influenza virus vaccines: need for clinical trials
F Krammer, P Palese - Nature immunology, 2014 - nature.com
Universal influenza virus vaccines: need for clinical trials | Nature Immunology Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …
content Thank you for visiting nature.com. You are using a browser version with limited support …
Influenza vaccination strategies: comparing inactivated and live attenuated influenza vaccines
S Sridhar, KA Brokstad, RJ Cox - Vaccines, 2015 - mdpi.com
Influenza is a major respiratory pathogen causing annual outbreaks and occasional
pandemics. Influenza vaccination is the major method of prophylaxis. Currently annual …
pandemics. Influenza vaccination is the major method of prophylaxis. Currently annual …
The unexpected impact of vaccines on secondary bacterial infections following influenza
AM Smith, VC Huber - Viral immunology, 2018 - liebertpub.com
Influenza virus infections remain a significant health burden worldwide, despite available
vaccines. Factors that contribute to this include a lack of broad coverage by current vaccines …
vaccines. Factors that contribute to this include a lack of broad coverage by current vaccines …
The immune response and within-host emergence of pandemic influenza virus
Zoonotic influenza viruses that are a few mutations away from pandemic viruses circulate in
animals, and can evolve into airborne-transmissible viruses in human beings. Paradoxically …
animals, and can evolve into airborne-transmissible viruses in human beings. Paradoxically …
Urgent challenges in implementing live attenuated influenza vaccine
A Singanayagam, M Zambon, A Lalvani… - The Lancet Infectious …, 2018 - thelancet.com
Conflicting reports have emerged about the effectiveness of the live attenuated influenza
vaccine. The live attenuated influenza vaccine appears to protect particularly poorly against …
vaccine. The live attenuated influenza vaccine appears to protect particularly poorly against …
The role of cell-mediated immunity against influenza and its implications for vaccine evaluation
Y Janssens, J Joye, G Waerlop, F Clement… - Frontiers in …, 2022 - frontiersin.org
Influenza vaccines remain the most effective tools to prevent flu and its complications.
Trivalent or quadrivalent inactivated influenza vaccines primarily elicit antibodies towards …
Trivalent or quadrivalent inactivated influenza vaccines primarily elicit antibodies towards …
Correlates of protection against influenza infection in humans—on the path to a universal vaccine?
CK Li, R Rappuoli, XN Xu - Current opinion in immunology, 2013 - Elsevier
Highlights•Influenza infection is prevented by protective antibodies.•Flu-specific T cells can
reduce viral load and disease severity.•Stem region of HA and flu internal proteins (NP and …
reduce viral load and disease severity.•Stem region of HA and flu internal proteins (NP and …