Curcumin stimulates UCP1-independent thermogenesis in 3T3-L1 white adipocytes but suppresses in C2C12 muscle cells

M Choi, S Mukherjee, JW Yun - Biotechnology and Bioprocess …, 2022 - Springer
Non-shivering thermogenesis may be an effective way to alter the energy balance in
adipocytes and skeletal muscle. Curcumin stimulates adipocyte browning and improves the …

Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model

D Zhao, Y Pan, N Yu, Y Bai, R Ma… - Royal Society …, 2021 - royalsocietypublishing.org
Accumulating evidence suggests that mitochondrial dysfunction and adipocyte
differentiation promote lipid accumulation in the development of obesity and diabetes …

Curcumin promotes browning of white adipose tissue in a norepinephrine-dependent way

S Wang, X Wang, Z Ye, C Xu, M Zhang, B Ruan… - Biochemical and …, 2015 - Elsevier
Brown adipose tissue converts energy from food into heat via the mitochondrial uncoupling
protein UCP1, defending against cold. In some conditions, inducible'brown-like'adipocytes …

Trans-anethole Induces Thermogenesis via Activating SERCA/SLN Axis in C2C12 Muscle Cells

S Mukherjee, M Choi, JW Yun - Biotechnology and Bioprocess …, 2022 - Springer
Recently, adaptive non-shivering thermogenesis has attracted considerable attention
because it can elevate energy expenditure and help treat obesity. Despite the numerous …

Capsaicin induces ATP-dependent thermogenesis via the activation of TRPV1/β3-AR/α1-AR in 3T3-L1 adipocytes and mouse model

AM Abdillah, JW Yun - Archives of Biochemistry and Biophysics, 2024 - Elsevier
Capsaicin (CAP) is a natural bioactive compound in chili pepper that activates the transient
receptor potential vanilloid subfamily 1 (TRPV1) and is known to stimulate uncoupling …

Inflammation downregulates UCP1 expression in brown adipocytes potentially via SIRT1 and DBC1 interaction

MK Nøhr, N Bobba, B Richelsen, S Lund… - International journal of …, 2017 - mdpi.com
Brown adipose tissue thermogenesis at the cost of energy is not only important for the
development of obesity, but also possesses great promise in anti-obesity treatment …

β-Carotene induces UCP1-independent thermogenesis via ATP-consuming futile cycles in 3T3-L1 white adipocytes

M Choi, JW Yun - Archives of Biochemistry and Biophysics, 2023 - Elsevier
The activation of brown fat and induction of beige adipocytes, so-called non-shivering
thermogenesis, is emerging as a promising target for therapeutic intervention in obesity …

Curcumin induces brown fat-like phenotype in 3T3-L1 and primary white adipocytes

J Lone, JH Choi, SW Kim, JW Yun - The journal of nutritional biochemistry, 2016 - Elsevier
Recent advances have been made in the understanding of pharmacological and dietary
agents that contribute to browning of white adipose tissue in order to combat obesity by …

[图书][B] Dietary curcumin intervention targets both white adipose tissue inflammation and brown adipose tissue thermogenesis

Z Song - 2017 - search.proquest.com
Increased adipose tissue inflammation and reduced energy expenditure are among the key
causative factors of obesity and its related metabolic disorders. Therapeutic tools targeting …

Highly Dispersible and Bioavailable Curcumin but not Native Curcumin Induces Brown‐Like Adipocyte Formation in Mice

S Nishikawa, M Kamiya, H Aoyama… - Molecular Nutrition & …, 2018 - Wiley Online Library
Scope The induction of brown‐like adipocytes in white adipose tissue (WAT) is a potential
therapeutic target for the treatment of obesity and metabolic disorders via the ability of these …