Secondary lymphoid tissues share the important function of bringing together antigens and
rare antigen‐specific lymphocytes to foster induction of adaptive immune responses. Peyer's …

Microfold (M) cells are located in the epithelium covering mucosa-associated lymphoid
tissues, such as the Peyer's patches (PPs) of the small intestine. M cells actively transport …

The gut represents a potential entry site for a wide range of pathogens including protozoa,
bacteria, viruses, or fungi. Consequently, it is protected by one of the largest and most …

Because Peyer's patches (PP) are the main inductive sites for gut IgA responses we have
focused this review on what we know about the function of PP germinal centers (GC). The …

Peyer's patches (PP) comprise transmucosal clusters of lymphoid follicles overlaid with a
specialized lympho-epithelium and consequently play a central role in the induction of …

In the Peyer's patches (PPs), germinal centers (GCs) are chronically induced by bacteria
and are the major sites for generation of gut immunoglobulin A (IgA) immune responses …

The gastrointestinal tract (GI tract) plays dual roles in human physiology: digestion and
uptake of nutrients and the more daunting task of maintaining immune homeostasis …

Whereas gut IgA responses to the microbiota may be multi-centered and diverse, little is
known about IgA responses to T-cell-dependent antigens following oral immunizations …

Backgound: Considering the important role of the Peyer's patches (PPs) in gut immune
balance, understanding of the detailed mechanisms that control and regulate the antigens in …

M cells located in the follicle-associated epithelium of Peyer's patches (PP) are shown to be
the principal sites for the sampling of gut luminal antigens. Thus, PP have long been …