Systematic review with network meta-analysis: antidiabetic medication and risk of hepatocellular carcinoma

YY Zhou, GQ Zhu, T Liu, JN Zheng, Z Cheng, TT Zou… - Scientific reports, 2016 - nature.com
Antidiabetic medication may modify the incidence of hepatocellular carcinoma (HCC). We
aimed to compare the use of different antidiabetic strategies and the incidence of HCC …

Anti-diabetic medications and the risk of hepatocellular cancer: a systematic review and meta-analysis

S Singh, PP Singh, AG Singh, MH Murad… - Official journal of the …, 2013 - journals.lww.com
Several preclinical and observational studies have shown that anti-diabetic medications
(ADMs) can modify the risk of hepatocellular cancer (HCC) in patients with diabetes mellitus …

[HTML][HTML] Metformin in the prevention of hepatocellular carcinoma in diabetic patients: a systematic review

V Cunha, HP Cotrim, R Rocha, K Carvalho… - Annals of hepatology, 2020 - Elsevier
Preventive effect of metformin in hepatocellular carcinoma (HCC) is not entirely clear. We
aimed to evaluate the use of metformin as a protective factor of HCC in diabetic patients.. We …

Impact of metformin use on risk and mortality of hepatocellular carcinoma in diabetes mellitus

Q Li, H Xu, C Sui, H Zhang - Clinics and Research in Hepatology and …, 2022 - Elsevier
Background The views regarding the associations between metformin use and
hepatocellular carcinoma (HCC) among diabetes mellitus (DM) patients are divisive. Thus …

Diabetes mellitus and risk of hepatocellular carcinoma: a systematic review and meta‐analysis

P Wang, D Kang, W Cao, Y Wang… - … metabolism research and …, 2012 - Wiley Online Library
Studies of diabetes and hepatocellular carcinoma (HCC) yielded inconsistent findings. This
meta‐analysis was conducted to examine the association between diabetes and risk of …

Metformin and reduced risk of hepatocellular carcinoma in diabetic patients: a meta-analysis

H Zhang, C Gao, L Fang, HC Zhao… - Scandinavian journal of …, 2013 - Taylor & Francis
Objectives. Recent epidemiological studies suggest that metformin treatment may reduce
the risks of cancer and overall cancer mortality among patients with diabetes mellitus (DM) …

Diabetes and insulin therapy, but not metformin, are related to hepatocellular cancer risk

L Miele, C Bosetti, F Turati, G Rapaccini… - Gastroenterology …, 2015 - Wiley Online Library
Introduction. Metabolic conditions, including type 2 diabetes, have been related to
hepatocellular carcinoma (HCC) risk. We have further analyzed the role of diabetes and …

Metformin for liver cancer prevention in patients with type 2 diabetes: a systematic review and meta-analysis

ZJ Zhang, ZJ Zheng, R Shi, Q Su… - The Journal of Clinical …, 2012 - academic.oup.com
Context: Data on the potential effect of metformin on the risk of liver cancer are limited and
inconsistent. Objective: The objective of this study was to review the evidence currently …

Effect of type 2 diabetes mellitus on the risk for hepatocellular carcinoma in chronic liver diseases: a meta-analysis of cohort studies

J Chen, Y Han, C Xu, T Xiao… - European Journal of …, 2015 - journals.lww.com
Questions remain about the relationship between type 2 diabetes mellitus (type 2 DM) and
the risk of hepatocellular carcinoma (HCC), especially in patients with chronic liver diseases …

Increased risk of hepatocellular carcinoma in patients with diabetes mellitus: a systematic review and meta‐analysis of cohort studies

C Wang, X Wang, G Gong, Q Ben, W Qiu… - … journal of cancer, 2012 - Wiley Online Library
In recent years, increasing evidence has suggested a strong association between diabetes
mellitus (DM) and hepatocellular carcinoma (HCC). To provide a quantitative assessment of …