Rodent models of post-traumatic stress disorder: behavioral assessment
Although the etiology and expression of psychiatric disorders are complex, mammals show
biologically preserved behavioral and neurobiological responses to valent stimuli which …
biologically preserved behavioral and neurobiological responses to valent stimuli which …
Current status of animal models of posttraumatic stress disorder: behavioral and biological phenotypes, and future challenges in improving translation
Increasing predictability of animal models of posttraumatic stress disorder (PTSD) has
required active collaboration between clinical and preclinical scientists. Modeling PTSD is …
required active collaboration between clinical and preclinical scientists. Modeling PTSD is …
Animal models of PTSD: a critical review
EI Flandreau, M Toth - Behavioral Neurobiology of PTSD, 2018 - Springer
The goals of animal research in post-traumatic stress disorder (PTSD) include better
understanding the neurophysiological etiology of PTSD, identifying potential targets for …
understanding the neurophysiological etiology of PTSD, identifying potential targets for …
Toward an animal model of posttraumatic stress disorder
A Siegmund, CT Wotjak - Annals of the New York Academy of …, 2006 - Wiley Online Library
Posttraumatic stress disorder (PTSD) belongs to the most frequent anxiety disorders.
Despite a broad body of evidence concerning neurobiological correlates of this illness, the …
Despite a broad body of evidence concerning neurobiological correlates of this illness, the …
Criteria for rationally evaluating animal models of postraumatic stress disorder
R Yehuda, SM Antelman - Biological psychiatry, 1993 - Elsevier
Animal models of stress have the potential to provide information about the course and
etiology of posttraumatic stress disorder (PTSD). To date, however, there have been no …
etiology of posttraumatic stress disorder (PTSD). To date, however, there have been no …
Animal models of post-traumatic stress disorder and recent neurobiological insights
Post-traumatic stress disorder (PTSD) is a complex psychiatric disorder characterized by the
intrusive re-experiencing of past trauma, avoidant behavior, enhanced fear, and …
intrusive re-experiencing of past trauma, avoidant behavior, enhanced fear, and …
The contribution of an animal model toward uncovering biological risk factors for PTSD
Clinical studies of posttraumatic stress disorder (PTSD) have elicited proposed risk factors
for developing PTSD in the aftermath of stress exposure. Generally, these risk factors have …
for developing PTSD in the aftermath of stress exposure. Generally, these risk factors have …
Animal model for PTSD: from clinical concept to translational research
In humans, the diagnosis of PTSD is made only if an individual exhibits a certain number of
symptoms from each of three quite well defined symptom clusters over a certain period of …
symptoms from each of three quite well defined symptom clusters over a certain period of …
Animal models of post-traumatic stress disorder: face validity
Post-traumatic stress disorder (PTSD) is a debilitating condition that develops in a proportion
of individuals following a traumatic event. Despite recent advances, ethical limitations …
of individuals following a traumatic event. Despite recent advances, ethical limitations …
Challenges in the use of animal models and perspectives for a translational view of stress and psychopathologies
NCB Barroca, G Della Santa, D Suchecki… - Neuroscience & …, 2022 - Elsevier
The neurobiology and development of treatments for stress-related neuropsychiatric
disorders rely heavily on animal models. However, the complexity of these disorders makes …
disorders rely heavily on animal models. However, the complexity of these disorders makes …