Role of diet in stem and cancer stem cells

F Puca, M Fedele, D Rasio, S Battista - International journal of molecular …, 2022 - mdpi.com
Diet and lifestyle factors greatly affect health and susceptibility to diseases, including cancer.
Stem cells' functions, including their ability to divide asymmetrically, set the rules for tissue …

[HTML][HTML] Dietary and metabolic control of stem cell function in physiology and cancer

MM Mihaylova, DM Sabatini, ÖH Yilmaz - Cell stem cell, 2014 - cell.com
Organismal diet has a profound impact on tissue homeostasis and health in mammals. Adult
stem cells are a keystone of tissue homeostasis that alters tissue composition by balancing …

Role of intra-and extracellular lipid signals in cancer stemness and potential therapeutic strategy

J Hu, L Zhang, W Chen, L Shen, J Jiang… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence showed that cancer stem cells (CSCs) play significant roles in
cancer initiation, resistance to therapy, recurrence and metastasis. Cancer stem cells …

[HTML][HTML] The nutritional phenome of EMT-induced cancer stem-like cells

E Cuyàs, B Corominas-Faja, JA Menendez - Oncotarget, 2014 - ncbi.nlm.nih.gov
The metabolic features of cancer stem (CS) cells and the effects of specific nutrients or
metabolites on CS cells remain mostly unexplored. A preliminary study to delineate the …

Unsaturated fatty acids maintain cancer cell stemness

A Mukherjee, HA Kenny, E Lengyel - Cell stem cell, 2017 - cell.com
Investigation of the metabolic regulation of cancer stem cells is an emerging field that offers
promising approaches for identifying and targeting recalcitrant stem cell populations. In this …

Metabolic features of cancer stem cells: the emerging role of lipid metabolism

R Mancini, A Noto, ME Pisanu, C De Vitis… - Oncogene, 2018 - nature.com
Cancer stem cells (CSCs) are an uncommon subset of tumor cells capable of self-renewal,
differentiating, and recreating the parental tumor when transplanted into the murine …

Fatty acid metabolites and the tumor microenvironment as potent regulators of cancer stem cell signaling

T Murai, S Matsuda - Metabolites, 2023 - mdpi.com
Individual cancer cells are not equal but are organized into a cellular hierarchy in which only
a rare few leukemia cells can self-renew in a manner reminiscent of the characteristic stem …

Metabolic plasticity of cancer stem cells in response to Microenvironmental cues

Y Xie, S Ma, M Tong - Cancers, 2022 - mdpi.com
Simple Summary Accumulating evidence indicates the existence of cancer stem cells
(CSCs) sub-populations which fuel cancer growth and maintain stemness in different …

Targeting cancer stem cells from a metabolic perspective

YA Shen, SC Pan, I Chu, RY Lai… - … Biology and Medicine, 2020 - journals.sagepub.com
The process of cancer development and progression is driven by distinct subsets of cancer
stem cells (CSCs) that contribute the self-renewal capacity as the major impetus to the …

The metabolic addiction of cancer stem cells

OS Sahoo, K Pethusamy, TP Srivastava… - Frontiers in …, 2022 - frontiersin.org
Cancer stem cells (CSC) are the minor population of cancer originating cells that have the
capacity of self-renewal, differentiation, and tumorigenicity (when transplanted into an …