Recent advancements of antiangiogenic combination therapies in ovarian cancer

D An, S Banerjee, JM Lee - Cancer treatment reviews, 2021 - Elsevier
Ovarian cancer is a deadly malignancy with a growing therapeutic armamentarium, though
achieving sustained benefit in the clinic remains largely elusive. Through biomarker and …

Antiangiogenic strategies in epithelial ovarian cancer: mechanism, resistance, and combination therapy

C Jin, M Yuan, H Bu, C Jin - Journal of Oncology, 2022 - Wiley Online Library
Angiogenesis is one of the hallmarks of cancer and plays a crucial role in carcinogenesis
and progression of epithelial ovarian cancer. Antiangiogenic agent is the first approved …

Novel therapeutics: response and resistance in ovarian cancer

D Zamarin - International Journal of Gynecologic Cancer, 2019 - ijgc.bmj.com
Here we review the latest pre-clinical and clinical developments for treatment of ovarian
cancer, presented at the American Association of Cancer Research/Rivkin Center Ovarian …

Antiangiogenic therapies in ovarian cancer

A Reinthaller - memo-Magazine of European Medical Oncology, 2016 - Springer
Angiogenesis plays a pivotal role in normal ovarian physiology as well as in the formation
and progression of ovarian cancer. Several well-designed phase II and III trials studied the …

Ovarian cancer treatments strategy: focus on PARP inhibitors and immune check point inhibitors

C Nero, F Ciccarone, A Pietragalla, S Duranti… - Cancers, 2021 - mdpi.com
Simple Summary Ovarian cancer treatment is the deadliest of gynecological cancers but the
introduction of target therapies in its therapeutic algorithm has significantly improved …

The role of targeted therapy in ovarian cancer

S Banerjee, S Kaye - European journal of cancer, 2011 - Elsevier
Ovarian cancer is the second most common gynaecological malignancy and the leading
cause of death from gynaecological cancer. Although in some cases treatment is initially …

Targeted therapy in ovarian cancer

HJ Lim, W Ledger - Women's Health, 2016 - journals.sagepub.com
Among female-specific cancers worldwide, ovarian cancer is the leading cause of death
from gynecologic malignancy in the western world. Despite radical surgery and initial high …

Targeted therapies for ovarian cancer

T Grunewald, JA Ledermann - Best practice & research Clinical obstetrics & …, 2017 - Elsevier
Epithelial ovarian cancer has the highest mortality rate of all gynaecological malignancies.
Most women present with advanced disease and develop a recurrence after radical surgery …

Anti-angiogenic agents in ovarian cancer: dawn of a new era?

J Liu, UA Matulonis - Current oncology reports, 2011 - Springer
Epithelial ovarian cancer is a leading cause of cancer-related death for women both in the
United States and worldwide, and the effectiveness of cytotoxic chemotherapy has …

Anti-angiogenesis for cancer: current status and prospects

M Russo, R Giavazzi - Thrombosis Research, 2018 - Elsevier
Since the establishment of tumor angiogenesis as a therapeutic target, new, effective
antiangiogenic agents have been developed. Despite their demonstrable clinical benefits …