The emerging roles of ferroptosis in organ fibrosis and its potential therapeutic effect
X Huang, Y Song, L Wei, J Guo, W Xu, M Li - International …, 2023 - Elsevier
Fibrosis refers to the process of excessive deposition of extracellular matrix (ECM) proteins,
eventually leading to excessive scar formation. Fibrotic diseases can occur in many organs …
eventually leading to excessive scar formation. Fibrotic diseases can occur in many organs …
Role of ferroptosis in fibrotic diseases
J Zhou, Y Tan, R Wang, X Li - Journal of Inflammation Research, 2022 - Taylor & Francis
Ferroptosis is a unique and pervasive form of regulated cell death driven by iron-dependent
phospholipid peroxidation. It results from disturbed cellular metabolism and imbalanced …
phospholipid peroxidation. It results from disturbed cellular metabolism and imbalanced …
Ferroptosis, a rising force against renal fibrosis
Y Liu, J Wang - Oxidative medicine and cellular longevity, 2022 - Wiley Online Library
Ferroptosis is a type of programmed cell death characterized by iron overload, oxidative
stress, imbalance in lipid repair, and mitochondria‐specific pathological manifestations …
stress, imbalance in lipid repair, and mitochondria‐specific pathological manifestations …
Physiological effects of ferroptosis on organ fibrosis
X Du, R Dong, Y Wu, B Ni - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
Ferroptosis is a new type of programmed cell death with unique morphological, biochemical,
and genetic features. From the initial study of histomorphology to the exploration of …
and genetic features. From the initial study of histomorphology to the exploration of …
Role of ferroptosis in fibrosis diseases
Z Sun, X Zou, M Bao, Z Huang, Y Lou, Y Zhang… - The American Journal of …, 2023 - Elsevier
Ferroptosis is a pervasive non-apoptotic mode of cell death that is different from autophagy
or necrosis. It is mainly caused by an imbalance between the production and degradation of …
or necrosis. It is mainly caused by an imbalance between the production and degradation of …
[HTML][HTML] Therapeutic implications of ferroptosis in renal fibrosis
Y Zhang, Y Mou, J Zhang, C Suo, H Zhou… - Frontiers in Molecular …, 2022 - frontiersin.org
Renal fibrosis is a common feature of chronic kidney disease (CKD), and can lead to the
destruction of normal renal structure and loss of kidney function. Little progress has been …
destruction of normal renal structure and loss of kidney function. Little progress has been …
[HTML][HTML] Ferroptosis and liver fibrosis
Q Pan, Y Luo, Q Xia, K He - International journal of medical …, 2021 - ncbi.nlm.nih.gov
Ferroptosis is an iron-dependent form of regulated cell death, which is characterized by a
large amount of lipid peroxide accumulation and the imbalance of redox state in cells …
large amount of lipid peroxide accumulation and the imbalance of redox state in cells …
[HTML][HTML] Ferroptosis interaction with inflammatory microenvironments: mechanism, biology, and treatment
J Dou, X Liu, L Yang, D Huang, X Tan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Ferroptosis is a newly discovered form of regulated cell death. Ferroptosis is an iron-
dependent lipid peroxidation reaction of cell membrane lipids, and it is closely related to the …
dependent lipid peroxidation reaction of cell membrane lipids, and it is closely related to the …
[HTML][HTML] Pharmacological modulation of ferroptosis as a therapeutic target for liver fibrosis
L Li, Z Zhu - Frontiers in Pharmacology, 2023 - frontiersin.org
Liver fibrosis, which is characterized by the excessive deposition of extracellular matrix
(ECM) materials (primarily fibrillar collagen-I), is an abnormal repair reaction and …
(ECM) materials (primarily fibrillar collagen-I), is an abnormal repair reaction and …
[HTML][HTML] The advancements in targets for ferroptosis in liver diseases
X Xiang, J Gao, D Su, D Shi - Frontiers in Medicine, 2023 - frontiersin.org
Ferroptosis is a type of regulated cell death caused by iron overload and lipid peroxidation,
and its core is an imbalance of redox reactions. Recent studies showed that ferroptosis …
and its core is an imbalance of redox reactions. Recent studies showed that ferroptosis …