Alzheimer's Disease (AD) and Type 2 diabetes mellitus (T2DM) are two incurable diseases
both hallmarked by an abnormal deposition of the amyloidogenic peptides Aβ and Islet …

The beta amyloid protein (Aβ) plays a central role in Alzheimer's disease (AD) pathogenesis
and its interaction with cell membranes in known to promote mutually disruptive structural …

Amyloid cytotoxicity, structure and polymorphisms are themes of increasing importance.
Present knowledge considers any peptide/protein able to undergo misfolding and …

Interest in amyloidogenesis has exploded in recent years, as scientists recognize the role of
amyloid protein aggregates in degenerative diseases such as Alzheimer's and Parkinson's …

Abnormal protein aggregation is a hallmark of various human diseases. α-Synuclein, a
protein implicated in Parkinson's disease, is found in aggregated form within Lewy bodies …

Several human degenerative diseases involve amyloidogenic peptides/proteins with high
conformational plasticity and propensity to self-aggregate into polymeric fibrillar assemblies …

The association of the amyloid-β (Aβ) peptide with cellular membranes is hypothesized to be
the underlying phenomenon of neurotoxicity in Alzheimer's disease. Misfolding of proteins …

Disruption of the integrity of the plasma membrane by amyloidogenic proteins is linked to the
pathogenesis of a number of common age-related diseases. Although accumulating …

Lipid membranes play a fundamental role in the pathological development of protein
misfolding diseases. Several pieces of evidence suggest that the lipid membrane could act …

Amyloid beta (Aβ) peptides, produced through endo-proteolytic cleavage of amyloid
precursor protein, are thought to be involved in the death of neural cells in Alzheimer's …