Background Data concerning the efficacy of bilateral prophylactic oophorectomy for
reducing the risk of gynecologic cancer in women with BRCA1 or BRCA2 mutations are …

BACKGROUND: The availability of genetic testing for inherited mutations in the BRCA1
gene provides potentially valuable information to women at high risk of breast or ovarian …

The availability of genetic testing for inherited mutations in the BRCA1 and BRCA2 genes
provides potentially valuable information to women at elevated risk of breast or ovarian …

The availability of genetic testing for inherited mutations in the BRCA1 or BRCA2 (BRCA1/2)
genes provides potentially valuable information to women at an elevated risk of breast or …

Purpose The purpose of this study was to estimate the extent of protection offered against
breast cancer by prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations and …

A retrospective study was performed to assess the histopathologic findings in high-risk
women undergoing bilateral prophylactic (salpingo)-oophorectomy. The medical files of …

Purpose Data on the efficacy of bilateral prophylactic mastectomy for breast cancer risk
reduction in women with BRCA1 and BRCA2 (BRCA1/2) mutations are limited, despite the …

PURPOSE: To review the findings at prophylactic oophorectomy of a series of women who
presented to a familial breast and ovarian cancer clinic. MATERIALS AND METHODS: Data …

ContextWomen with BRCA1 or BRCA2 mutation are often advised to undergo preventive
oophorectomy. The effectiveness of this intervention has not been prospectively evaluated in …

Objective. To ascertain the frequency of significant pathologic alterations in prophylactic
oophorectomy specimens in high-risk women referred to a tertiary care center. Methods …