The original model for regulation of oocyte maturation proposed by us in 1978 postulated
that gap junction-mediated transmission of cAMP from the follicle cells to the oocyte inhibits …

We have reexamined the possibility that cumulus cell cAMP can enter the oocyte via the gap
junctions connecting the two cell types (Schultz et al., 1983a). Since our recent results …

The cyclic adenosine monophosphate (cAMP) content of intact oocyte‐cumulus cell
complexes at various times after the induction of oocyte maturation in mice in vivo was …

Experiments were performed to determine if elevation of cumulus cell cAMP results in an
increase in mouse oocyte cAMP while the heterologous gap junctions were intact. Both …

The possible mediatory role of cAMP in the induction of oocyte maturation by luteinizing
hormone (LH) is not yet clear since evidence for both inhibitory and stimulatory actions of the …

The purpose of the present review is to outline the current understanding on the molecular
mechanisms governing various stages of oocyte maturation, transition from maternal to …

Fully grown, but not growing, mammalian oocytes spontaneously resume meiosis in vitro.
Resumption of meiosis, also known as oocyte maturation, is associated with a drop in …

The source of the inhibitory levels of cAMP that maintain oocytes meiotically arrested is
under controversy. A model for regulation of the meiotic division that suggests the transfer of …

The hypothesis that cumulus cells inhibit oocyte maturation by a cAMP-dependent process
was tested (RM Schultz, R. Montgomery, PF Ward-Bailey, and JJ Eppig (1983). Dev. Biol …

Meiotically arrested mammalian oocytes are stimulated to resume meiosis by LH. This
response, which can be reversed by elevation of intraoocyte cAMP levels, is associated with …