Chemotherapeutic efficacy of curcumin and resveratrol against cancer: Chemoprevention, chemoprotection, drug synergism and clinical pharmacokinetics

S Patra, B Pradhan, R Nayak, C Behera, L Rout… - Seminars in cancer …, 2021 - Elsevier
The frequent inefficiency of conventional cancer therapies due to drug resistance, non-
targeted drug delivery, chemotherapy-associated toxic side effects turned the focus to …

Curcumin based nanomedicines as efficient nanoplatform for treatment of cancer: new developments in reversing cancer drug resistance, rapid internalization, and …

S Khan, M Imran, TT Butt, SWA Shah, M Sohail… - Trends in Food Science …, 2018 - Elsevier
Background Cancer is a group of diseases involving an abnormal growth of cells which tend
to proliferate in an uncontrolled fashion and in some cases metastasize to the surrounding …

[HTML][HTML] Polychemotherapy with curcumin and doxorubicin via biological nanoplatforms: enhancing antitumor activity

M Ashrafizadeh, A Zarrabi, F Hashemi, A Zabolian… - Pharmaceutics, 2020 - mdpi.com
Doxorubicin (DOX) is a well-known chemotherapeutic agent extensively applied in the field
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …

Advances in dietary phenolic compounds to improve chemosensitivity of anticancer drugs

A Bouyahya, NE Omari, S Bakrim, NE Hachlafi… - Cancers, 2022 - mdpi.com
Simple Summary Several dietary phenolic compounds isolated from medicinal plants exert
significant anticancer effects via several mechanisms. They induce apoptosis, autophagy …

Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects

AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

Underlying anticancer mechanisms and synergistic combinations of phytochemicals with cancer chemotherapeutics: potential benefits and risks

M Ayaz, A Nawaz, S Ahmad, OF Mosa… - Journal of Food …, 2022 - Wiley Online Library
Cancer therapies are associated with various challenges including the emergence of
multidrug resistant tumors, toxicological issues, severe side effects, and economic burden …

Curcumin in cancer therapy: A novel adjunct for combination chemotherapy with paclitaxel and alleviation of its adverse effects

M Ashrafizadeh, A Zarrabi, F Hashemi, ER Moghadam… - Life sciences, 2020 - Elsevier
Dealing with cancer is of importance due to enhanced incidence rate of this life-threatening
disorder. Chemotherapy is an ideal candidate in overcoming and eradication of cancer. To …

New insights into curcumin-and resveratrol-mediated anti-cancer effects

A Arena, MA Romeo, R Benedetti, L Masuelli, R Bei… - Pharmaceuticals, 2021 - mdpi.com
Curcumin and resveratrol are bioactive natural compounds displaying anti-inflammatory,
anti-oxidant and anti-cancer properties. In this study, we compared the cytotoxic effects of …

Co‐administration of curcumin with other phytochemicals improves anticancer activity by regulating multiple molecular targets

N Ghobadi, A Asoodeh - Phytotherapy Research, 2023 - Wiley Online Library
Natural plant phytochemicals are effective against different types of diseases, including
cancer. Curcumin, a powerful herbal polyphenol, exerts inhibitory effects on cancer cell …

Phytochemicals in cancer cell chemosensitization: Current knowledge and future perspectives

E Khatoon, K Banik, C Harsha, BL Sailo… - Seminars in Cancer …, 2022 - Elsevier
Despite significant advancements made in the treatment of cancer during the past several
decades, it remains one of the leading causes of death worldwide killing approximately 9.6 …