[HTML][HTML] Breath biopsy assessment of liver disease using an exogenous volatile organic compound—toward improved detection of liver impairment

G Ferrandino, I Orf, R Smith, M Calcagno… - Clinical and …, 2020 - journals.lww.com
METHODS: We compared the exhaled breath of 40 controls, 32 cirrhotic patients, and 12
cirrhotic patients with HCC using the Breath Biopsy platform. Breath samples were analyzed …

[HTML][HTML] Breath Biopsy® to Identify Exhaled Volatile Organic Compounds Biomarkers for Liver Cirrhosis Detection

G Ferrandino, G De Palo, A Murgia… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Methods To identify candidate biomarkers we compared 46 breath samples from cirrhosis
patients and 42 from controls. Collection and analysis used Breath Biopsy OMNI™ …

[HTML][HTML] Volatile biomarkers in breath associated with liver cirrhosis—comparisons of pre-and post-liver transplant breath samples

RF Del Río, ME O'Hara, A Holt, P Pemberton, T Shah… - …, 2015 - thelancet.com
Background The burden of liver disease in the UK has risen dramatically and there is a need
for improved diagnostics. Aims To determine which breath volatiles are associated with the …

Limonene in exhaled breath is elevated in hepatic encephalopathy

ME O'Hara, RF Del Río, A Holt… - Journal of breath …, 2016 - iopscience.iop.org
Breath samples were taken from 31 patients with liver disease and 30 controls in a clinical
setting and proton transfer reaction quadrupole mass spectrometry (PTR-Quad-MS) used to …

[HTML][HTML] A profile of volatile organic compounds in exhaled air as a potential non-invasive biomarker for liver cirrhosis

KE Pijls, A Smolinska, DMAE Jonkers, JW Dallinga… - Scientific reports, 2016 - nature.com
Early diagnosis of liver cirrhosis may prevent progression and development of
complications. Liver biopsy is the current standard, but is invasive and associated with …

Isoprene in the exhaled breath is a novel biomarker for advanced fibrosis in patients with chronic liver disease: a pilot study

N Alkhouri, T Singh, E Alsabbagh… - Clinical and …, 2015 - journals.lww.com
OBJECTIVES: Analysis of volatile organic compounds (VOCs) in the exhaled breath can
identify markers for alcoholic and nonalcoholic fatty liver disease. The aim of this pilot study …

Breath biomarkers of liver cirrhosis

J Dadamio, S Van den Velde, W Laleman… - … of Chromatography B, 2012 - Elsevier
The diagnosis of asymptomatic cirrhosis in patients with liver disease is of importance to
start screening for complications in due time. Liver biopsy is neither sensitive nor practical …

The breathprints in patients with liver disease identify novel breath biomarkers in alcoholic hepatitis

IA Hanouneh, NN Zein, F Cikach, L Dababneh… - Clinical …, 2014 - Elsevier
Background & Aims Selected-ion flow-tube mass spectrometry can precisely identify trace
gases in the human breath, in the parts-per-billion range. We investigated whether …

Limonene in expired lung air of patients with liver disease

MI Friedman, G Preti, RO Deems, LS Friedman… - Digestive diseases and …, 1994 - Springer
As part of an effort to examine the relationship between chemosensory disturbance and oral
chemistry, we analyzed expired lung air samples from a series of 24 patients with liver …

[HTML][HTML] Volatomic analysis identifies compounds that can stratify non-alcoholic fatty liver disease

R Sinha, KA Lockman, NZM Homer, E Bower… - JHEP Reports, 2020 - Elsevier
Background & aims Analysis of volatile organic compounds (VOCs) in exhaled
breath,'volatomics', provides opportunities for non-invasive biomarker discovery and novel …