Wuhan, China

R Juan, R Akbarzadeh, K Guan… - Immune-Mediated …, 2023 - books.google.com
Atopic dermatitis (AD) is one of the most common allergic diseases in children, with a
prevalence of more than 20% in high-income countries, which seriously affects the life …

Dupilumab in pediatric dermatology

KM Plachouri, S Georgiou - Journal of Dermatological Treatment, 2022 - Taylor & Francis
Background Dupilumab is a monoclonal antibody that targets the interleukin (IL)-4 receptor
alpha subunit of the IL-4 and IL-13 receptor. This novel agent has received a license for the …

Safety of dupilumab in a 5‐month‐old infant with severe atopic dermatitis

SA Havele, MC Khurana, P McMahon… - Pediatric …, 2022 - Wiley Online Library
Dupilumab is a fully humanized monoclonal antibody that suppresses Th2‐mediated
inflammation by inhibiting signaling of interleukin‐4 and interleukin‐13 through the …

Real-life effectiveness and safety of dupilumab in adolescents with atopic dermatitis: a 52-week single-center retrospective study

L Gargiulo, CA Vignoli, L Ibba, A Cortese… - Journal of …, 2023 - Taylor & Francis
Atopic dermatitis (AD) is a chronic inflammatory skin disease principally characterized by
type 2 inflammation, skin barrier dysfunction, and itch (1). In developed countries, it affects …

27350 Dupilumab improves Eczema Area and Severity Index regional scores across all anatomical regions in children aged 6–11 years with severe atopic dermatitis …

AS Paller, MJ Cork, D Marcoux, A Wollenberg… - Journal of the American …, 2021 - jaad.org
Background: AD, a chronic inflammatory skin disease, can affect different parts of the body.
Dupilumab inhibits interleukin (IL)-4 and IL-13 signaling and is approved for treating multiple …

Efficacy and safety of dupilumab in pediatric patients with moderate to severe atopic dermatitis: a real-world study

DY Yang, L Li, T Lu, WW Jing, X Liu, XL Li - Archives of Dermatological …, 2023 - Springer
Dupilumab is the first human monoclonal antibody that treats atopic dermatitis (AD) by
blocking interleukin 4 (IL-4) and interleukin 13 (IL-13), which can suppress the Th2 …

[HTML][HTML] Real-world experience of long-term dupilumab treatment for atopic dermatitis in Korea

DH Lee, HC Ko, CH Na, JY Roh, KY Park… - Annals of …, 2022 - ncbi.nlm.nih.gov
Dear Editor: Dupilumab, a human monoclonal antibody against interleukin (IL)-4 receptor α,
is the first biologic therapy approved for the treatment of patients with moderate to severe …

Case report: The application of dupilumab in atopic dermatitis children complicated with nephrotic syndrome

YQ Yang, H Chen, LR Qiu, RF Zhu - Frontiers in Medicine, 2022 - frontiersin.org
Nephrotic syndrome (NS) tends to be more common in patients with history of allergies.
Atopic dermatitis (AD) is one of the most common allergic diseases in children. Dupilumab, a …

Efficacy of dupilumab in children 6 months to 11 years old with atopic dermatitis: a retrospective real-world study in China

N Yang, Y Ye, J Shao, H Wu, Q Xu, J Zhu, J Liu, Z Li - Dermatitis®, 2024 - liebertpub.com
Background: Atopic dermatitis (AD) is a common skin disease that affects patients' quality of
life, especially in the pediatric population. Dupilumab has shown good efficacy and safety in …

The less‐known face of dupilumab: its role in mesenchymal stem cells by interleukin‐13 modulation

A Campanati, M Di Vincenzo, G Radi… - British Journal of …, 2021 - academic.oup.com
Three of 20 patients (15%) reported mild gastrointestinal side-effects (gastric pain, nausea
or diarrhoea) not related to Clostridium difficile colitis. For two of three patients with …