Genetic testing in patients with unexplained coronary aneurysms or dilation

D Adlam, FS van Dijk, B Loeys - European Heart Journal, 2024 - academic.oup.com
Coronary artery dilation [defined in CAAR (Coronary Artery Aneurysm Registry) as a
diameter exceeding 1.5× an adjacent normal coronary segment or the largest normal artery] …

Genetics of spontaneous coronary artery dissection gains new momentum

C Grond-Ginsbach, ST Engelter - Circulation: Genomic and …, 2018 - Am Heart Assoc
2 Circ Genom Precis Med. 2018; 11: e002148. DOI: 10.1161/CIRCGEN. 118.002148 April
2018 ants of 29 genes were analyzed, with 16 genes tested in> 50% of the sample …

Complex Genetic Architecture of Spontaneous Coronary Artery Dissection

P Natarajan, SM Day - JAMA cardiology, 2024 - jamanetwork.com
Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of
nonatherosclerotic myocardial infarction. Clinical risk factors for SCAD include younger age …

Spontaneous coronary artery dissection and its association with heritable connective tissue disorders

S Henkin, SM Negrotto, MS Tweet, S Kirmani… - Heart, 2016 - heart.bmj.com
Objective Spontaneous coronary artery dissection (SCAD) is an under-recognised but
important cause of myocardial infarction and sudden cardiac death. We sought to determine …

Prospective cardiovascular genetics evaluation in spontaneous coronary artery dissection

MI Kaadan, C MacDonald, F Ponzini… - Circulation: Genomic …, 2018 - Am Heart Assoc
Background: Previous studies describing genetics evaluation in spontaneous coronary
artery dissection (SCAD) have been retrospective in nature or presented as single case …

[HTML][HTML] Advancements in the genetics of spontaneous coronary artery dissection

AE Katz, SK Ganesh - Current Cardiology Reports, 2023 - Springer
Abstract Purpose of Review Spontaneous coronary artery dissection (SCAD) is a significant
cause of acute myocardial infarction that is increasingly recognized in young and middle …

Familial spontaneous coronary artery dissection: evidence for genetic susceptibility

K Goel, M Tweet, TM Olson, JJ Maleszewski… - JAMA internal …, 2015 - jamanetwork.com
Importance Spontaneous coronary artery dissection (SCAD) is a major cause of acute
coronary syndrome in young women, especially among those without traditional …

Recent advances on the genetics of spontaneous coronary artery dissection

A Amrani-Midoun, D Adlam… - Circulation: Genomic and …, 2021 - Am Heart Assoc
Spontaneous coronary artery dissection (SCAD) has been acknowledged as a significant
cause of acute myocardial infarction, predominantly in young to middle-aged women. SCAD …

Burden of rare genetic variants in spontaneous coronary artery dissection with high-risk features

Y Wang, A Starovoytov, AM Murad, KL Hunker… - JAMA …, 2022 - jamanetwork.com
Importance The emerging genetic basis of spontaneous coronary artery dissection (SCAD)
has been defined as both partially complex and monogenic in some patients, involving …

P5539 Genetic heterogeneity of spontaneous coronary artery dissection (SCAD)

L Giuliani, A Di Toro, E Disabella… - European Heart …, 2019 - academic.oup.com
Introduction SCAD is a rare coronary event that may cause acute coronary syndromes
(ACS). SCAD predominantly occurs in apparently healthy, young to middle aged women (up …