[HTML][HTML] Novel drugs with high efficacy against tumor angiogenesis

S Qi, S Deng, Z Lian, K Yu - International Journal of Molecular Sciences, 2022 - mdpi.com
Angiogenesis is involved in physiological and pathological processes in the body. Tumor
angiogenesis is a key factor associated with tumor growth, progression, and metastasis …

[HTML][HTML] Angiogenic signaling pathways and anti-angiogenic therapy for cancer

ZL Liu, HH Chen, LL Zheng, LP Sun… - Signal transduction and …, 2023 - nature.com
Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

AT-533, a novel Hsp90 inhibitor, inhibits breast cancer growth and HIF-1α/VEGF/VEGFR-2-mediated angiogenesis in vitro and in vivo

PC Zhang, X Liu, MM Li, YY Ma, HT Sun… - Biochemical …, 2020 - Elsevier
The inhibition of angiogenesis is suggested to be an attractive strategy for cancer
therapeutics. Heat shock protein 90 (Hsp90) is closely related to tumorigenesis as it …

[HTML][HTML] Angiogenesis: managing the culprits behind tumorigenesis and metastasis

AHS Yehya, M Asif, SH Petersen, AV Subramaniam… - Medicina, 2018 - mdpi.com
Deregulated angiogenesis has been identified as a key contributor in a number of
pathological conditions including cancer. It is a complex process, which involves highly …

[PDF][PDF] Tumor angiogenesis and molecular targets for therapy

Y Cao - Front Biosci, 2009 - article.imrpress.com
[Frontiers in Bioscience 14, 3962-3973, January 1, 2009] 3962 Tumor angiogenesis and
molecular targets for therapy Yihai Cao Lab Page 1 [Frontiers in Bioscience 14, 3962-3973 …

[HTML][HTML] Broad targeting of angiogenesis for cancer prevention and therapy

Z Wang, C Dabrosin, X Yin, MM Fuster, A Arreola… - Seminars in cancer …, 2015 - Elsevier
Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Targeting tumor micro-environment for design and development of novel anti-angiogenic agents arresting tumor growth

RN Gacche, RJ Meshram - Progress in biophysics and molecular biology, 2013 - Elsevier
Angiogenesis: a process of generation of new blood vessels has been proved to be
necessary for sustained tumor growth and cancer progression. Inhibiting angiogenesis …

[HTML][HTML] Tumor angiogenesis and anti-angiogenic strategies for cancer treatment

RI Teleanu, C Chircov, AM Grumezescu… - Journal of clinical …, 2019 - mdpi.com
Angiogenesis is the process through which novel blood vessels are formed from pre-existing
ones and it is involved in both physiological and pathological processes of the body …

Tumor angiogenesis–a potential target in cancer chemoprevention

TA Bhat, RP Singh - Food and chemical toxicology, 2008 - Elsevier
Tumor angiogenesis is critically important for the growth of solid tumors as tumors remain in
dormant phase for a long time in the absence of the initiation of blood vessel formation …

Angiogenesis in spontaneous tumors and implications for comparative tumor biology

C Benazzi, A Al-Dissi, CH Chau… - The Scientific World …, 2014 - Wiley Online Library
Blood supply is essential for development and growth of tumors and angiogenesis is the
fundamental process of new blood vessel formation from preexisting ones. Angiogenesis is …