Recently, the concept of the brain-gut-microbiota (BGM) axis disturbances in the
pathogenesis of Alzheimer's disease (AD) has been receiving growing attention. At the …

With the acceleration of global population aging, neurodegenerative diseases (NDs) will
become the second leading cause of death in the world, which seriously threatens human …

Recent epidemiological and molecular studies have linked the disruption of cholesterol
homeostasis to increased risk for developing Alzheimer's disease (AD). Emerging evidence …

Introduction Increasing evidence suggests a role for the gut microbiome in central nervous
system disorders and a specific role for the gut-brain axis in neurodegeneration. Bile acids …

Alzheimer's disease (AD) and related dementias (ADRD) are still a serious global public
health concern more than a century after the German neuropathologist and psychiatrist Dr …

The burden of neurological and neuropsychiatric disorders continues to grow with significant
impacts on human health and social economy worldwide. Increasing clinical and preclinical …

Recent investigations have increased the interest on the connection between the
microorganisms inhabiting the gut (gut microbiota) and human health. An imbalance of the …

Alzheimer's disease (AD) is a neurodegenerative process characterized by loss of neurons
in the hippocampus and cerebral cortex, leading to progressive cognitive decline …

Bile acids (BAs) are amphiphilic steroidal molecules generated from cholesterol in the liver
and facilitate the digestion and absorption of fat-soluble substances in the gut. Some BAs in …

Alzheimer's disease (AD) is one of the most frequently diagnosed neurodegenerative
disorders worldwide and poses a major challenge for both affected individuals and their …