[PDF][PDF] Combination therapy with rosuvastatin and fenofibric acid for mixed dyslipidemia: overview of efficacy and safety

TA Jacobson, PH Jones, EM Roth - Clinical Lipidology, 2010 - researchgate.net
Despite achieving optimal LDL-C levels with statin therapy, the risk of cardiovascular events
persists in the majority of dyslipidemic patients. In particular, patients with mixed …

One-year efficacy and safety of rosuvastatin+ fenofibric acid combination therapy in patients with mixed dyslipidemia: evaluation of dose response

KC Ferdinand, MH Davidson, MT Kelly… - American Journal of …, 2012 - Springer
Background Statins are the standard-of-care therapy for reducing low-density lipoprotein
cholesterol (LDL-C) levels; however, combination with other lipid-modifying agents may be …

Simultaneous achievement of optimal lipid levels with the combination of fenofibric acid and rosuvastatin in patients with mixed dyslipidemia

MH Davidson, PH Jones, A Lele… - Journal of Clinical …, 2009 - lipidjournal.com
Patients with mixed (atherogenic) dyslipidemia have multiple lipid abnormalities, including
low HDL-C and elevated TG, LDL-C, non-HDL-C, and ApoB. Single agent lipid therapy may …

Efficacy and safety of rosuvastatin 5 mg in combination with fenofibric acid 135 mg in patients with mixed dyslipidemia–a phase 3 study

EM Roth, RS Rosenson, DM Carlson… - … drugs and therapy, 2010 - Springer
Background Patients with mixed dyslipidemia characterized by elevated low-density
lipoprotein cholesterol (LDL-C), elevated triglycerides (TG), and reduced high-density …

Attainment of goal/desirable lipid levels in patients with mixed dyslipidemia after 12 weeks of treatment with fenofibric acid and rosuvastatin combination therapy: A …

EM Roth, RS Rosenson, PH Jones… - Journal of Clinical …, 2012 - Elsevier
BACKGROUND: Goal/desirable lipid levels are underachieved in patients with mixed
dyslipidemia. These patients may have substantial residual risk of cardiovascular disease …

Rosuvastatin and fenofibrate combination in the treatment of mixed hyperlipidemia: a narrative review

K Biswas, A Tiwari, P Jadhav, A Goel… - Journal of Current …, 2021 - cmro.in
Introduction: Patients with mixed dyslipidemia are presented with high levels of low-density
lipid cholesterol (LDL-C), triglycerides (TG), and reduced high-density lipid cholesterol (HDL …

Fenofibric acid plus statin combination therapy for the treatment of mixed dyslipidemia

PH Jones - Clinical Lipidology and Metabolic Disorders, 2009 - search.proquest.com
Patients with mixed dyslipidemia have a higher risk of atherosclerotic coronary heart
disease than patients with isolated elevated LDL-C. Evidence-based guidelines target LDL …

A review on the rationale and clinical use of concomitant rosuvastatin and fenofibrate/fenofibric acid therapy

JD Strain, DK Farver, JR Clem - Clinical pharmacology: advances …, 2010 - Taylor & Francis
Mixed dyslipidemia, characterized by a lipid triad of elevated triglycerides (TG), elevated low-
density lipoprotein-cholesterol (LDL-C) and reduced high-density lipoprotein-cholesterol …

High doses of rosuvastatin are superior to low doses of rosuvastatin plus fenofibrate or n-3 fatty acids in mixed dyslipidemia

AP Agouridis, V Tsimihodimos, TD Filippatos… - Lipids, 2011 - Springer
The aim of the study was to compare the efficacy of high-dose rosuvastatin, low-dose
rosuvastatin plus fenofibrate and low-dose rosuvastatin plus omega-3 fatty acids with regard …

Comparison of switch to the highest dose of rosuvastatin vs. add‐on nicotinic acid vs. add‐on fenofibrate for mixed dyslipidaemia

A Kei, EN Liberopoulos… - International journal of …, 2013 - Wiley Online Library
Background Use of a statin at a standard dose may be insufficient for the treatment of mixed
dyslipidaemia. Whether switch to the highest dose of rosuvastatin (40 mg) or add‐on …