Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Intracellular delivery of materials has become a critical component of genome-editing
approaches, ex vivo cell-based therapies, and a diversity of fundamental research …

The intracellular delivery of proteins is of great significance. For diseases such as cancer,
heart disease and neurodegenerative diseases, many important pharmacological targets …

Intracellular delivery of materials is a challenge in research and therapeutic applications.
Physical methods of plasma membrane disruption have recently emerged as an approach to …

With advances in therapeutic science, apart from drugs, newer bioactive moieties like
oligonucleotides, proteins, peptides, enzymes and antibodies are constantly being …

Intracellular delivery is considered an indispensable process for various studies, ranging
from medical applications (cell‐based therapy) to fundamental (genome‐editing) and …

Protein-based therapeutics have unique therapeutic potential due to their specificity,
potency, and low toxicity. The vast majority of intracellular applications of proteins require …

Cell delivery reagents often exploit the endocytic pathway as a route of cell entry. Once
endocytosed, these reagents must overcome endosomal entrapment to ensure the release …

Ineffective cellular delivery is a common problem in numerous biological applications.
Developing delivery reagents that work robustly in a variety of experimental settings remains …

Efficient cellular delivery of biologically active molecules is one of the key factors that affect
the discovery and development of novel drugs. The plasma membrane is the first barrier that …