Therapeutic pipeline for atopic dermatitis: end of the drought?

AS Paller, K Kabashima, T Bieber - Journal of Allergy and Clinical …, 2017 - Elsevier
Until the past year, our therapeutic armamentarium for treating atopic dermatitis (AD) was
still primarily topical corticosteroids and, for more severe disease, systemic …

New treatments in atopic dermatitis

N Puar, R Chovatiya, AS Paller - Annals of Allergy, Asthma & Immunology, 2021 - Elsevier
Objective To discuss the efficacy and safety of novel and emerging topical and systemic
therapeutic agents for atopic dermatitis (AD). Data Sources The review of the published …

Novel insights into atopic dermatitis

CF Schuler IV, AC Billi, E Maverakis, LC Tsoi… - Journal of Allergy and …, 2023 - Elsevier
Recent research into the pathophysiology and treatment of atopic dermatitis (AD) has shown
notable progress. An increasing number of aspects of the immune system are being …

Efficacy of biologics in atopic dermatitis

J Wu, E Guttman-Yassky - Expert Opinion on Biological Therapy, 2020 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is a heterogeneous disease. Recent advancements in
understanding AD pathogenesis resulted in the exponential expansion of its therapeutic …

New treatments for atopic dermatitis targeting beyond IL-4/IL-13 cytokines

Y Renert-Yuval, E Guttman-Yassky - Annals of Allergy, Asthma & …, 2020 - Elsevier
Objective Atopic dermatitis (AD) is an increasingly common inflammatory skin disease
undergoing significant revolution in recent years. New data on disease pathogenesis …

[HTML][HTML] Expert perspectives on management of moderate-to-severe atopic dermatitis: a multidisciplinary consensus addressing current and emerging therapies

M Boguniewicz, AF Alexis, LA Beck, J Block… - The Journal of Allergy …, 2017 - Elsevier
Atopic dermatitis (AD) is a common, chronic, relapsing, inflammatory skin disease that
affects children and adults. Until recently, the only Food and Drug Administration–approved …

Advances in the pathophysiology of atopic dermatitis revealed by novel therapeutics and clinical trials

X Yang, N Kambe, R Takimoto-Ito… - Pharmacology & …, 2021 - Elsevier
Atopic dermatitis (AD) is an inflammatory skin disease arising from a complex interplay of
genetic, immune, and environmental factors. The development and successful marketing of …

Impact of a decade of research into atopic dermatitis

PD Arkwright, JJ Koplin - The Journal of Allergy and Clinical Immunology …, 2023 - Elsevier
The last decade has seen an unprecedented pace of change, particularly of clinical
research in atopic dermatitis (AD). This review summarizes some key discoveries. Over the …

Understanding the immune landscape in atopic dermatitis: The era of biologics and emerging therapeutic approaches

M Moyle, F Cevikbas, JL Harden… - Experimental …, 2019 - Wiley Online Library
Atopic dermatitis (AD) is a chronic, systemic, inflammatory disease that affects the skin and is
characterized by persistent itch and marked redness. AD is associated with an increased …

Atopic dermatitis: an expanding therapeutic pipeline for a complex disease

T Bieber - Nature reviews Drug discovery, 2022 - nature.com
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a complex
pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains …