We investigated the role of the vascular endothelium in the local production of angiotensin.
Angiotensin release from isolated rat hindquarters perfused with an artificial medium was …

We investigated the effect of angiotensin II (ANG II) and enalapril on accumulation of renin
messenger RNA (mRNA) and on renal renin distribution (immunohistochemical analysis) …

The cleavage of synthetic tetradecapeptide renin substrate has been used to infer the
presence of renin in the walls of isolated blood vessels; however, the conversion of natural …

To investigate the regulatory mechanism of the vascular renin-angiotensin system, we
perfused isolated rat hind legs with plasma-free buffer and quantified angiotensin peptides …

Local vascular generation of angiotensin was investigated in isolated perfused rat
hindquarters. Extraction and combined high-performance liquid chromatography (HPLC) …

The effects of specific renin inhibitors, angiotensin converting enzyme inhibitors,
indomethacin, and prostaglandin I2 analogue on the release of angiotensins from isolated …

We tested the hypothesis that angiotensinases limit the spillover of locally formed
angiotensin II into the circulation. The release of angiotensin peptides from isolated rat …

To examine and characterize the vascular renin-angiotensin system in low-renin models of
renal hypertension with and without the presence of overt renal insufficiency, we studied the …

Angiotensin synthesis at tissue sites is well-established, and depends largely, if not
completely, on kidney-derived renin. The exact tissue site of angiotensin generation …

To define whether intrarenal renin and angiotensinogen synthesis and distribution are
affected by angiotensin-converting enzyme (ACE) inhibition, a control group of adult, male …