Intracerebral haemorrhage expansion: definitions, predictors, and prevention

A Morotti, G Boulouis, D Dowlatshahi, Q Li… - The Lancet …, 2023 - thelancet.com
Haematoma expansion affects a fifth of patients within 24 h of the onset of acute
intracerebral haemorrhage and is associated with death and disability, which makes it an …

Small intracerebral haemorrhages are associated with less haematoma expansion and better outcomes

D Dowlatshahi, EE Smith, ML Flaherty… - … Journal of Stroke, 2011 - journals.sagepub.com
Background and purpose Haematoma expansion following intracerebral haemorrhage is a
major determinant of early neurological worsening and poor clinical outcome. This has …

Predicting hematoma expansion after primary intracerebral hemorrhage

HB Brouwers, Y Chang, GJ Falcone, X Cai… - JAMA …, 2014 - jamanetwork.com
Importance Many clinical trials focus on restricting hematoma expansion following acute
intracerebral hemorrhage (ICH), but selecting those patients at highest risk of hematoma …

Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational …

AM Demchuk, D Dowlatshahi… - The Lancet …, 2012 - thelancet.com
Background In patients with intracerebral haemorrhage (ICH), early haemorrhage
expansion affects clinical outcome. Haemostatic treatment reduces haematoma expansion …

Defining hematoma expansion in intracerebral hemorrhage: relationship with patient outcomes

D Dowlatshahi, AM Demchuk, ML Flaherty, M Ali… - Neurology, 2011 - AAN Enterprises
Background: Hematoma expansion (HE) is a surrogate marker in intracerebral hemorrhage
(ICH) trials. However, the amount of HE necessary to produce poor outcomes in an …

[HTML][HTML] Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data

RAS Salman, J Frantzias, RJ Lee, PD Lyden… - The Lancet …, 2018 - thelancet.com
Background Intracerebral haemorrhage growth is associated with poor clinical outcome and
is a therapeutic target for improving outcome. We aimed to determine the absolute risk and …

Association between hypodensities detected by computed tomography and hematoma expansion in patients with intracerebral hemorrhage

G Boulouis, A Morotti, HB Brouwers… - JAMA …, 2016 - jamanetwork.com
Importance Hematoma expansion is a potentially modifiable predictor of poor outcome
following an acute intracerebral hemorrhage (ICH). The ability to identify patients with ICH …

The HEP score: a nomogram-derived hematoma expansion prediction scale

X Yao, Y Xu, E Siwila-Sackman, B Wu, M Selim - Neurocritical care, 2015 - Springer
Background Identification of intracerebral hemorrhage (ICH) patients at risk of substantial
hematoma expansion (SHE) could facilitate the selection of candidates likely to benefit from …

Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study

C Delcourt, Y Huang, H Arima, J Chalmers, SM Davis… - Neurology, 2012 - AAN Enterprises
Objective: Uncertainty exists over the size of potential beneficial effects of medical
treatments targeting hematoma growth in intracerebral hemorrhage (ICH). We report …

Early deterioration, hematoma expansion, and outcomes in deep versus lobar intracerebral hemorrhage: the FAST trial

LR Kuohn, J Witsch, T Steiner, KN Sheth, H Kamel… - Stroke, 2022 - Am Heart Assoc
Background: In patients with intracerebral hemorrhage (ICH), it is unclear whether early
neurological deterioration, hematoma expansion (HE), and outcome vary by supratentorial …