Gestational diabetes mellitus (GDM) has been shown to be associated with high risk of
diabetes in offspring. However, the mechanisms involved and the possibilities of …

Our study investigated whether a deterioration of glucose homeostasis and insulin secretion
in adult female rats from hyperglycemic dams could be transmitted to the next generation …

Intrauterine growth restriction (IUGR) increases susceptibility to age-related diseases,
including type 2 diabetes (T2DM), and is associated with permanent and progressive …

Aims/hypothesis The familial predisposition to Type 2 diabetes mellitus is mediated by both
genetic and intrauterine environmental factors. In the normal course of events, maternal …

OBJECTIVE—Low birth weight (LBW) is associated with increased risk of obesity, diabetes,
and cardiovascular disease during adult life. Moreover, this programmed disease risk can …

Maternal diabetes has adverse effects not only on oocyte quality but also on embryo
development. However, it is still unknown whether the DNA imprinting in oocytes is altered …

Diabetes mellitus (DM) is a heterogeneous group of disorders whose common trait is
chronic hyperglycemia. Gestational diabetes mellitus (GDM) is one of the subtypes of DM …

This study was designed to assess the effect of maternal diabetes in rats on serum glucose
and insulin concentrations, insulin resistance, histological architecture of pancreas and …

There is a global epidemic of obesity and diabetes, and current efforts to curb the diabetes
epidemic have had limited success. Epidemiological studies have highlighted increased risk …

IGF2 loss of imprinting (LOI) is fairly prevalent and implicated in the pathogenesis of human
cancer and developmental disease; however, the causes of this phenomenon are largely …