Epidemiology and pathophysiology of malignancy in common variable immunodeficiency?

AT Manesh, G Azizi, A Heydari, F Kiaee… - Allergologia et …, 2017 - Elsevier
Common variable immunodeficiency (CVID) is a diagnostic category of primary
immunodeficiency (PID) which may present with heterogeneous disorders including …

[HTML][HTML] Common variable immunodeficiency-associated cancers: the role of clinical phenotypes, immunological and genetic factors

L Bruns, V Panagiota, S von Hardenberg… - Frontiers in …, 2022 - frontiersin.org
Objective The aim of this study was to investigate the prevalence of cancer and associating
clinical, immunological, and genetic factors in a German cohort of patients with common …

Malignancy in common variable immunodeficiency: a systematic review and meta-analysis

F Kiaee, G Azizi, H Rafiemanesh… - Expert review of …, 2019 - Taylor & Francis
Background: Common variable immunodeficiency (CVID) is the most common clinically
significant primary immunodeficiency (PID) disorder characterized by variable clinical …

Lymphoid malignancy in common variable immunodeficiency in a single‐center cohort

T Smith, C Cunningham‐Rundles - European journal of …, 2021 - Wiley Online Library
One of the complications of common variable immunodeficiency (CVID) is the development
of lymphoid malignancy. In this retrospective, single‐center study of 647 CVID subjects …

Malignancies are the major cause of death in patients with adult onset common variable immunodeficiency

I Quinti, C Agostini, S Tabolli, G Brunetti… - Blood, The Journal …, 2012 - ashpublications.org
In the paper by Resnick et al, the authors clearly defined lymphoma, lung impairment,
hepatitis, and gastrointestinal disease as the main causes of mortality in 411 subjects with …

[HTML][HTML] Lymphoproliferative disease and cancer among patients with common variable immunodeficiency

S Gangemi, A Allegra, C Musolino - Leukemia research, 2015 - Elsevier
Innate immune deficiencies are a heterogeneous group of genetically inherited diseases
affecting the innate and adaptive immune systems that confer susceptibility to infection …

[HTML][HTML] Altered spectrum of lymphoid neoplasms in a single-center cohort of common variable immunodeficiency with immune dysregulation

C Wehr, L Houet, S Unger, G Kindle… - Journal of clinical …, 2021 - Springer
Purpose Common variable immune deficiency (CVID) confers an increased risk of lymphoid
neoplasms, but reports describing the precise WHO specification of the lymphoma subtypes …

[HTML][HTML] CVID-associated tumors: Czech nationwide study focused on epidemiology, immunology, and genetic background in a cohort of patients with CVID

P Kralickova, T Milota, J Litzman, I Malkusova… - Frontiers in …, 2019 - frontiersin.org
Background: Common variable immunodeficiency disorder (CVID) is one of the most
frequent inborn errors of immunity, increased occurrence of malignancies, particularly …

[HTML][HTML] Non-infectious complications of common variable immunodeficiency: updated clinical spectrum, sequelae, and insights to pathogenesis

H Ho, C Cunningham-Rundles - Frontiers in immunology, 2020 - frontiersin.org
Non-infectious complications in common variable immunodeficiency (CVID) have emerged
as a major clinical challenge. Detailed clinical spectrum, organ-specific pathologies and …

[HTML][HTML] Common variable immunodeficiency (CVID): new genetic insight and unanswered questions

HD Ochs - Clinical and Experimental Immunology, 2014 - ncbi.nlm.nih.gov
Common variable immunodeficiency (CVID) is a clinically and molecularly heterogeneous
disorder with a varied clinical presentation [1]. The age of onset varies from early childhood …